Diamonds and sperm: a new way to detect fertility problems?
NCT ID NCT05514223
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new technique called diamond magnetometry to measure free radicals in individual sperm cells and blood. Free radicals are natural but can damage sperm if out of balance. Researchers will also look at the bacteria in semen and how lifestyle and diet affect free radical levels. The goal is to better understand what causes male infertility and possibly find new ways to diagnose it.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a new way to diagnose male infertility by measuring free radicals in sperm, and may help identify lifestyle factors that affect fertility.
- What could go wrong
- This is an early observational study with only 80 participants, so results may not apply to all men. The new measurement technique is still experimental and may not prove useful in practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Males of couples visiting the CRM of the UMCG
- Ages
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18 to 55 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males of couples visiting the CRM at the UMCG between 18-55 years old. * Planned semen-analysis as standard care. Exclusion Criteria: * Males who receive(d) chemo- and/or radiotherapy, use(d) testosterone suppletion and/or anabolic steroids * Males who are azoospermic * Males who have an abnormal SA due to genetic causes. * Semen analysis with round cells \>2x106 /ml (as marker for infection) * Males who currently use antibiotics
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Medical Centre Groningen
RECRUITINGGroningen, Provincie Groningen, 9713GZ, Netherlands
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- Can virtual reality goggles take the sting out of a fertility procedure?