New drug may boost IVF success by thickening uterine lining
NCT ID NCT07499817
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether pentoxyfilline, a drug that improves blood flow, can thicken the uterine lining and increase pregnancy rates in women with unexplained infertility undergoing frozen embryo transfer. About 100 women with good-quality embryos will receive the drug or a placebo. The main goal is to see if more women become pregnant with this treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2023
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 43 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * as good quality day five frozen embryos. Exclusion Criteria: * history of endocrine diseases, * history of any previous surgery that couldm compromise the integrity of endometrium, * cardiovascular, renal and liver diseases,
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
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A doctor treating you
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Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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Beni-suef university Hospital
RECRUITINGBanī Suwayf, Beni Suweif Governorate, 62521, Egypt
Contact Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Do infertility treatments leave a metabolic mark on children?
- Could a Woman's biological clock also predict her Heart's future?
- Sperm sorting showdown: can a microchip pick the best sperm for pregnancy?
- Could your genes predict when fertility fades?
- Can virtual reality goggles take the sting out of a fertility procedure?