The University Of Texas Health Science Center, Houston

This study tests whether semaglutide, a drug used for diabetes and weight loss, can help people with cocaine use disorder reduce their cocaine use. About 75 adults will receive semaglutide along with counseling. Researchers will measure changes in brain responses to cocaine-relat…

This study tests whether giving a common stomach acid drug (pantoprazole) early after severe bleeding from injury can help prevent kidney damage. About 100 adults with hemorrhagic shock will be randomly assigned to receive the drug either early or at the usual time. Researchers w…

This study tests a new way to repair open spine defects (spina bifida) in newborns right after birth. Surgeons will use a patch made from the baby's own umbilical cord to cover the opening in the spine. The goal is to see if this patch helps the wound heal better, reduces fluid l…

This study tests a new device called ViTrack that measures blood pressure continuously without needles. It will be used on 40 adults having surgery who already need standard invasive blood pressure monitoring. The goal is to see how well the device matches the usual method and to…

This study tests whether a non-invasive brain stimulation technique called rTMS can improve negative symptoms (like lack of motivation or emotion) in people with schizophrenia. Twenty adults with schizophrenia spectrum disorders will receive either real or sham stimulation to spe…

This study looks at whether adding a medicine called Ketorolac to the usual pain treatment helps children drink more fluids after cleft palate surgery. About 74 children with cleft palate (with or without cleft lip) will take part. The goal is to see if better pain control leads …

This study tests whether a non-invasive brain stimulation technique called rTMS can help people with schizophrenia spectrum disorder quit smoking. Fifty participants will receive active stimulation using one of two coil types, and researchers will track changes in smoking habits …

This study tests a 4-week program that teaches people in rural areas how to use ear acupressure (a non-needle technique) to manage chronic pain in the back, neck, knees, or other joints. Participants use a smartphone app to learn self-treatment and are compared to a group that on…

This study looks at whether a safe, non-invasive ear stimulator (taVNS) can be used together with arm and hand exercises to help people with incomplete cervical spinal cord injury. The main goal is to see if the approach is safe and practical, with only 12 adults taking part. If …

This study aims to understand how the brain works differently in people with PTSD, especially regarding anxiety and hypervigilance. Researchers will use brain scans and EEG to measure brain activity. They will also test a non-invasive brain stimulation technique called tACS to se…

This study looks at donated blood to see if it contains high levels of a protein called pTau217, which is linked to Alzheimer's disease. Researchers want to know if blood transfusions might pass on this risk to recipients. About 250 blood donors will provide samples for testing.

This study is gathering information from 1500 people with cluster headache or trigeminal neuralgia to better understand these painful conditions. Researchers will collect surveys, genetic samples, and other health data. The goal is to find patterns and markers that could lead to …