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Could a common supplement help rare brain vessel disorder?

NCT ID NCT06280482

Recruiting now Disease control Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 27 times

Summary

This early-stage study tests nicotinamide riboside (NR), a form of vitamin B3, in 15 people with smooth muscle dysfunction syndrome (SMDS) — a rare genetic condition that can cause moyamoya-like narrowing of brain arteries. Researchers want to see if NR improves blood flow to the brain, thinking, and daily symptoms, and whether it is safe. Participants take NR daily for a set period and undergo tests like brain scans, cognitive assessments, and blood work.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

SMOOTH MUSCLE DYSFUNCTION SYNDROME (SMDS)