Humidity showdown: can 90% humidity save tiny preemies?
NCT ID NCT06399861
First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This study compares two humidity levels (70% vs 90%) in incubators for extremely premature infants born before 25 weeks. The goal is to see if higher humidity reduces dehydration and improves survival without increasing health problems. About 350 babies will take part, and researchers will track weight loss, fluid balance, and a composite safety score.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Incubator humidity (70% or 90% relative humidity)
- What this could lead to
- If it works, this could establish a safer standard for incubator humidity, reducing dehydration and complications in extremely premature infants.
- What could go wrong
- This is a relatively early-stage trial with 350 participants, and the two humidity levels may show no meaningful difference in survival or safety. Results may not apply to all premature infants.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Memorial Hermann Hospital
RECRUITINGHouston, Texas, 77030, United States
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Nationwide Children's Hospital - Grant Medical Center
RECRUITINGColumbus, Ohio, 43205, United States
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Nationwide Children's Hospital - Ohio State University Wexner Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
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North Central Baptist Hospital
RECRUITINGSan Antonio, Texas, 78258, United States
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Sharp Mary Birch Hospital for Women & Newborns
RECRUITINGSan Diego, California, 92123, United States
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St. Luke's Baptist Hospital
RECRUITINGSan Antonio, Texas, 78229, United States
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Texas Children's Hospital
RECRUITINGHouston, Texas, 77030, United States
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The University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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The Woman's Hospital of Texas
RECRUITINGHouston, Texas, 77054, United States
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