The University Of Texas Health Science Center, Houston

This study looks at how well a new device called GentleWave cleans out infected tissue from deep inside root canals. Researchers will examine 50 extracted human molars under a microscope to see how much pulp tissue and bacteria remain after the procedure. The goal is to improve r…

This study tests a surgical technique called uterosacral ligament suspension during a minimally invasive hysterectomy (vNOTES). The goal is to see if adding this step can prevent the vagina from collapsing later (prolapse), a common problem after hysterectomy. About 50 women havi…

This study tests a new, non-invasive treatment using low-intensity focused ultrasound (LIFU) to help people quit smoking. It targets deep brain areas linked to nicotine addiction without surgery or medication. The study will enroll 100 smokers who have tried to quit at least 3 ti…

This study looks at whether offering a rapid HIV and syphilis test to pregnant women in the emergency department helps find more infections and start treatment faster. About 1,400 pregnant women who have not had regular prenatal care or prior testing will be included. The goal is…

This study tests whether giving free, healthy food (fruits and vegetables) to pregnant women at high risk for gestational diabetes can prevent the condition. Researchers will enroll 400 women receiving care at Harris Health clinics who are early in pregnancy and have risk factors…

This study aims to improve care for teens and young adults who have experienced sexual assault. Researchers will work with survivors and experts to create a program that offers same-day HIV prevention medicine and substance use support. The study will test if this program is prac…

This study tests a testosterone gel applied to the skin to see if it can safely improve low sexual desire and arousal in women going through or past menopause. About 150 women aged 40-65 with diagnosed low libido will receive either the gel or a placebo for several months. The go…

This study tests whether a virtual home rehabilitation program helps stroke survivors in underserved Texas communities recover better than standard care alone. About 80 adults who recently had a stroke and are returning home will take part. The program uses video sessions to guid…

This study tests a 16-week exercise program designed for Hispanic adults with multiple sclerosis who have walking problems. Participants will either join the exercise group or a waitlist. The goal is to see if the program improves walking ability and quality of life. About 66 peo…

This study tests a personalized version of a therapy called Stepped Care Cognitive Behavioral Therapy for Children after Trauma (SC-CBT-CT) for Latino children aged 7-12 with PTSD. The goal is to see if tailoring the treatment to each family's needs improves symptoms and access t…

This study looks at whether using a special brain monitor (BIS) can help people on breathing machines in the ICU. The monitor tracks sedation levels, which may help doctors give just the right amount of medicine. Researchers want to see if this leads to shorter time on the ventil…

This study looks at whether a procedure called microneedling radiofrequency (which uses tiny needles and heat) can improve skin and fat thickness in the face, and if adding a topical cream (poly-L-lactic acid) makes it work better. About 30 adults seeking facial rejuvenation will…

This study tests a personalized version of a proven trauma therapy for Latino children ages 7-12 with PTSD. The approach starts with a lower-intensity treatment and adds more support only if needed, making care more accessible. Researchers will measure changes in trauma symptoms …

This study looks at how the drug Fintepla changes brain blood flow and breathing in people with Dravet Syndrome, a severe form of epilepsy. About 25 participants will have brain scans before and after taking Fintepla to see if it improves the brain's response to carbon dioxide. T…

This study looks at how often people develop allergic skin reactions to two different wound dressings used after open shoulder surgery: one made from silk protein and another from a medical glue mesh. About 350 adults having shoulder surgery will be randomly assigned to one dress…

This study tests a simple screening tool to help doctors find muscle stiffness (spasticity) sooner in stroke patients. Researchers will check if the tool helps speed up referrals and treatment. About 80 adults who recently had a stroke will take part for up to 24 months.

This study compares continuous vital sign monitoring using a wearable sensor to standard intermittent checks in adults after major non-cardiac surgery. The goal is to see if constant monitoring reduces serious complications. 492 participants will be randomly assigned to either bl…

This study measures how raising or lowering the jaw (the space between upper and lower teeth) changes the shape of the lower face and lip positions. Researchers will study 50 adults who wear full dentures or overdentures. The goal is to understand these changes better, not to tes…

This study tests whether a virtual reality (VR) program that combines thinking and physical exercises is easy to use and acceptable for people with mild memory problems. Ten participants will try the VR activities and report on usability, comfort, and any side effects. The goal i…

This study is testing a mobile app designed to help Latino young adults with autism and their parents during the move to adulthood. The app is available in both English and Spanish. Researchers want to see if the app is easy to use, helpful, and practical for families. About 30 p…

This study looks at whether a program called MAGIC, which adds short physical activity breaks and lessons into the school day, can help elementary students be more active and lower their risk for heart problems. Researchers will track how well teachers use the program and measure…

This study explores whether artificial intelligence (AI) can give helpful feedback to doctors-in-training (residents) about how they talk with patients. About 64 general surgery residents will use an AI tool to review their conversations and see if it improves clarity and underst…

This study aims to improve how schools adopt programs that prevent bullying and teen dating violence. Researchers will adapt an existing online tool and test it with about 25 school staff members in Texas. The goal is to see if the tool is easy to use and helps staff feel more co…