The University Of Texas Health Science Center, Houston

This study looked at whether pioglitazone, a drug used for diabetes, can help people who recently stopped using cocaine stay off the drug when combined with talk therapy. 61 adults with cocaine use disorder took part. The goal was to see if the drug improves brain health and redu…

This study tested two common blood pressure medications in 70 women who had high blood pressure after giving birth. One group took a combined pill (hydrochlorothiazide/lisinopril) and the other took nifedipine. The goal was to see which pill controlled blood pressure better in th…

This study looked at whether adding a special light therapy (antimicrobial photodynamic therapy) to standard deep cleaning helps treat gum disease. Twenty adults with deep gum pockets and bleeding were treated on both sides of the mouth—one side got the light therapy, the other d…

This study tested whether teaching kids with asthma and their families through social media (like Facebook and Instagram) could reduce hospital visits and school absences. 200 children hospitalized for asthma took part. The goal was to see if this approach lowers healthcare costs…

This study tested a virtual culinary medicine program for 89 adults with type 2 diabetes and high body mass index. Participants took online cooking classes to learn healthy eating habits. Researchers measured changes in blood sugar (HbA1c), weight, and cholesterol to see if the p…

This study tested a rapid point-of-care test for syphilis and HIV in pregnant women at clinics in Guatemala. The goal was to see if this quick test could increase screening and treatment rates, ultimately preventing passing these infections to babies. The study enrolled 149 women…

This study looked at whether using a continuous glucose monitor (CGM) to screen for gestational diabetes is better than the usual test. Over 1,600 pregnant women participated. The goal was to see if CGM screening leads to fewer health problems for babies and lower healthcare cost…

This study tested whether giving the acid-reducing drug pantoprazole during heart surgery could prevent acute kidney injury, a common complication. One hundred adults at moderate-to-high risk for kidney damage were randomly assigned to receive either pantoprazole or another acid …

This study tested a program called CATCH My Breath to see if it could prevent middle school students from starting to use e-cigarettes. About 1,400 students from 20 schools took part over three years. Half the schools used the program, and the other half used standard tobacco pre…

This study tested a program that gives healthy food incentives and coaching to adults at risk for diabetes. The goal was to help them stick with healthy habits and lower their chances of getting diabetes. 61 participants joined the program, and researchers tracked weight, blood s…

This study tested an internet-based program called 'Me & You-Tech' designed to prevent dating violence in 6th graders. The program involved students, parents, and schools. Researchers measured whether the program reduced how many teens hurt or were hurt by a dating partner.

This study tested a probiotic (BB-12 with LGG) in 123 children with autism and stomach problems. The goal was to see if different doses are safe and can improve behavior and gut health. Researchers tracked side effects, behavior changes, and gut bacteria over 56 days of treatment…

This study tested two different medical skin glues (2-Octylcyanoacrylate and n-butyl-2-cyanoacrylate) used to close small cuts from laparoscopic or robotic abdominal surgery. The goal was to see which glue causes less contact dermatitis (redness or rash) around the incision. 180 …

This study looked at 260 people having emergency stroke treatment to see if being awake with sedation or fully asleep under general anesthesia leads to better recovery. The goal was to find out which approach reduces disability and improves quality of life three months after the …

This study tested whether a natural compound called palmitoylethanolamide (PEA) can help reduce depression in people with bipolar disorder. 34 adults who were already taking a mood stabilizer took part. Researchers measured changes in depression scores and looked at how the body'…

This study tested a 16-week exercise program designed for wheelchair users with multiple sclerosis. Researchers wanted to see if the program was safe, doable, and liked by participants. They also checked if it improved symptoms and overall health. The study involved 24 people who…

This study looked at whether taking estrogen pills along with a type of talk therapy called prolonged exposure (PE) can improve PTSD symptoms in women. 83 women aged 18-45 with PTSD took part. They were randomly assigned to receive either estrogen or a placebo pill with their the…

This study tested whether raising a patient's legs before general anesthesia can prevent a sudden drop in blood pressure. Researchers studied 200 adults undergoing surgery. The goal was to see if this simple technique reduces the need for emergency medications and keeps the heart…

This study tested whether a special tissue graft called ActiveMatrix works better than the usual steroid injection for frozen shoulder. 56 adults with frozen shoulder received either the graft or a steroid shot, and researchers tracked their pain and disability over 6 months. The…

This small pilot study tested whether pairing vagus nerve stimulation with rehabilitation is safe and feasible for people with cervical spinal cord injury. Six participants with incomplete injuries received the nerve stimulation device surgically and then completed rehab sessions…

This study looked at whether people with spinal cord injuries can safely do high-intensity walking exercise using a wearable robotic exoskeleton. Eleven participants completed five training sessions, and researchers measured heart rate and walking improvements. The goal was to se…

This early study tested whether a safe, mild electrical brain stimulation device (tDCS) could be used at home to help with behavioral symptoms like agitation or apathy in people with Alzheimer's disease. Only 3 people took part, and the main goal was to see if the treatment was a…

This study tested whether spraying lidocaine into the breathing tube before suctioning can prevent dangerous spikes in brain pressure in children with severe traumatic brain injury. Ten children in intensive care received either lidocaine spray, lidocaine drops, or saltwater drop…

This study tested whether exenatide, a drug used for diabetes, can help people quit smoking and prevent the weight gain that often happens after quitting. 140 adults who smoked at least 5 cigarettes daily and wanted to quit took part. They received either exenatide or a placebo a…

This study tested whether suvorexant, a sleep aid, could help smokers manage cravings, withdrawal, and stress that often lead to relapse. Fourteen non-treatment-seeking smokers took the drug or a placebo and were monitored for stress reactions, smoking urges, and sleep quality. T…

This study looked at whether giving the muscle relaxant methocarbamol through a vein can help control pain and lower the amount of opioid painkillers needed in the first 6 hours after spine surgery. Over 1,200 adults having elective spine surgery took part. Researchers tracked th…

This study looked at whether the drug crofelemer can reduce chronic diarrhea in people without HIV whose diarrhea has no clear cause. It also checked which standard tests are best at finding treatable reasons for the diarrhea. About 93 adults took part, and the main goal was to s…

This study looked at 20 mothers who had a previous child with jaundice needing treatment. Researchers wanted to see if waiting longer to clamp the umbilical cord after birth would lead to higher bilirubin levels (a marker for jaundice) in the newborn. The goal was to better under…

This study looked at 255 women who chose to have permanent sterilization (tubal ligation) surgery. Researchers compared three different surgical approaches to see which one led to the best recovery and highest patient satisfaction. The goal was to help doctors and patients choose…

This study surveyed nearly 2,500 people diagnosed with cluster headache to learn which treatments work best and what they think about new options. Participants filled out one online questionnaire. The goal was to gather patient views, not to test a new drug or device.

This study surveyed 803 people diagnosed with new daily persistent headache (NDPH) to learn about their headache patterns and what treatments they have tried. Participants completed an online questionnaire about their symptoms and experiences. The goal was to gather information t…

This study tested a program that used community health workers and text messages to encourage COVID-19 testing and vaccination in vulnerable populations. A total of 384 adults with smartphones took part. The goal was to see if this approach could increase testing and vaccination …

This study tested a new approach to help people with dementia and their caregivers reduce unnecessary medications. Researchers compared patients who received care focused on their personal health priorities to those who got usual care. The goal was to see if this method leads to …

This study tested whether a short screening tool could help hospital staff identify older adults who are experiencing abuse, neglect, or financial exploitation. Researchers worked with 100 patients in a special geriatric unit to see how often the tool was used and how many people…

This study looked at ways to help elementary school teachers include physical activity in their daily lessons. Researchers worked with 301 teachers and students from kindergarten to 5th grade to see if a special plan could make it easier for teachers to keep using active learning…

This study looked at whether using a semi-structured checklist when anesthesia providers change shifts during surgery can lower the risk of serious problems like heart attack, kidney injury, pneumonia, or death. Over 3,700 adults having non-cardiac surgery took part. The goal was…

This study tested a faster way to give anesthesia medicines to help place a breathing tube more quickly. It included 154 adults who were overweight or had a higher risk of difficult intubation. Researchers compared the new method to the standard approach to see which worked bette…

This study tested a positive parenting program for 28 homeless women who had experienced violence from a partner. The program aimed to reduce parenting stress and improve emotional support, self-confidence, and children's behavior. Researchers measured changes using questionnaire…