The University Of Texas Health Science Center, Houston

This study was designed to see if a device called RetroPerc could help doctors reach and remove large kidney stones more easily. It planned to enroll adults with kidney stones larger than 10 mm. However, the study was withdrawn before any participants were enrolled, so no results…

This study tests a community program in Houston that combines outreach, medication, counseling, and peer support to help people with opioid use disorder start and stay in treatment. About 3,000 adults who test positive for opioids and want to stop using will take part. The goal i…

This study looks at whether giving a higher dose of vitamin D (800 IU per day) to extremely premature infants (born before 28 weeks or weighing less than 1000 grams) improves their health compared to the usual dose. Researchers will check vitamin D levels and measure effects on t…

This study compares a comprehensive program of lifestyle changes, cholesterol-lowering drugs, and advanced PET heart scans against standard medical care for people with stable coronary artery disease. Over 1,000 participants will be followed for five years to see which approach b…

This study tests whether giving extremely preterm babies less intravenous (IV) fat (lipids) can lower harmful bilirubin levels and protect their brain development. Bilirubin can build up in these tiny infants and cause hearing loss or long-term disabilities. Researchers will comp…

This study follows 100 people with pancreatic cysts or tumors who receive a treatment called EUS-guided radiofrequency ablation (RFA). A thin tube with a camera is used to deliver heat directly to the lesion to destroy it. The goal is to see how well the procedure works and track…

This study tests a brain pacemaker (deep brain stimulation) for people with severe depression that hasn't improved with other treatments. About 16 adults aged 22-70 will receive the implant, which sends electrical pulses to a specific brain area. The goal is to safely reduce depr…

This study tests a new way to repair spina bifida in the womb using a special patch made from donated human umbilical cord tissue. The surgery is done through tiny cuts (fetoscopic) to cover the spinal defect and prevent fluid leaks. About 50 pregnant women carrying babies with s…

This study tests a lifestyle program called Healthy Liver/Hígado Sano for Hispanic patients with metabolic-dysfunction associated steatotic liver disease (MASLD), also known as fatty liver disease. The program includes education sessions and family support to help participants lo…

This study tests a video-based telehealth program for stroke survivors to help them manage their blood pressure at home. About 542 adults who had a stroke or mini-stroke and have high blood pressure will take part. The goal is to see if this approach improves blood pressure contr…

This study looks at whether giving extra vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) improves their lung, bone, immune, and brain health. About 180 babies will receive either the extra vitamin D or usual care for the…

This study uses a special camera and a safe dye to take pictures of the lymphatic system, which helps move fluid in the body. Researchers want to see how this system works in healthy people and in those with conditions like lymphedema or lipedema. The goal is to find patterns tha…

This study tests if starting physiotherapy early can prevent lymphedema (swelling) in people treated for head and neck cancer. Twenty survivors will either use a home compression device or receive standard care. Researchers will compare how many develop swelling over one year.

This study tests whether pressing specific points on the ear (auricular point acupressure) can reduce pain, numbness, and tingling caused by chemotherapy. About 225 cancer patients will try this non-needle technique. Researchers will also measure changes in nerve function and bod…

This study was designed to test a new, more precise way to treat atrial fibrillation (an irregular heartbeat) using a technique called pulmonary vein myocardial sleeve ablation guided by omnipolar mapping. The goal was to see if this approach could shorten procedure time and redu…

This study is testing whether a high-quality, high-dose, and high-intensity arm therapy program can help people who had a stroke at least 6 months ago improve arm movement and daily function. Nine participants will undergo intensive therapy and be assessed with MRI scans and move…

This study was designed to observe how a small, disposable ultrasound probe placed in the esophagus could help doctors make decisions about treating patients with unstable blood pressure. The plan was to enroll 60 adults in the trauma or heart surgery intensive care unit. However…

This study follows 1,500 young people over time to learn what factors—like personal attitudes, relationships, and neighborhood—lead to gun access, carrying, or use. It also includes in-depth interviews with known gun carriers. The goal is to identify risks and protective factors …

This study looks at how the brain learns to be afraid and how it learns to avoid things. About 150 healthy adults will look at pictures on a screen and sometimes get a mild shock. By measuring brain waves and sweat, researchers hope to understand the brain circuits involved in fe…

This study looks at what to do when a surgeon finds a small, hidden groin hernia during a routine hernia repair. It compares fixing it right away versus just watching it over time. The goal is to help patients and doctors decide the best approach by creating a simple decision-mak…

This study tests an online group program designed to help people with spinal cord injury (SCI) stay healthy as they age. Researchers will enroll 180 adults who have had a traumatic SCI for at least 15 years or are over 45, and who use a wheelchair. The program focuses on improvin…

This study aimed to see if giving antibiotics to pregnant people whose water broke very early (before 22 weeks) could delay delivery and improve baby health. It was planned for people with a single baby and no active labor. However, the study was withdrawn before enrolling anyone…

This study looks at how headaches work by measuring molecules in the blood and tears. Researchers will use capsaicin (from chili peppers) and ice water to trigger mild pain or eye watering in people with headaches and healthy volunteers. The goal is to find better ways to diagnos…

This study looks at whether a new program can help community health clinics better care for cancer survivors. Over 5,500 patients and their clinicians will take part. The goal is to see if the program increases screening for new cancers and improves how well doctors understand su…

This study looks at whether a special compression device can help improve fluid drainage in the legs of people with chronic vein disease. About 34 adults with leg swelling will either receive standard compression bandages alone or bandages plus daily use of an advanced pneumatic …

This study tests a program that offers housing and on-site employment to adults who are at risk of homelessness. Researchers want to see if this approach reduces emergency room visits and improves housing stability, employment, and quality of life. About 750 participants will be …

This study planned to use low-intensity focused ultrasound to temporarily change brain activity in healthy volunteers and see how it affects emotion processing. The goal was to understand brain function and check safety, not to treat any disease. However, the study was withdrawn …

This study aimed to see if patients who drink clear liquids up to one hour before gallbladder surgery have similar stomach fluid levels as those who fast overnight. It also looked at scheduling flexibility, patient satisfaction, and side effects like nausea and vomiting. The stud…

This study looks at whether a mobile app-based rehab program, supported by a community health worker, can help stroke survivors in the Rio Grande Valley recover at home. Eleven uninsured adults who had a recent first stroke will try the program for a few months. Researchers will …