Zapping the brain to bring back joy: new study for bipolar depression

NCT ID NCT05240352

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a gentle brain stimulation technique called tDCS to see if it can improve anhedonia—the loss of interest or pleasure—in people with bipolar depression. About 45 adults with bipolar disorder and significant anhedonia will receive tDCS while researchers use brain scans to track changes in reward-related brain pathways. The goal is to understand if this personalized approach can ease symptoms and improve quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anhedonia bipolar depression bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••