Seoul National University Hospital

This study tests the drug maribavir in 20 adults with multiple myeloma or lymphoma who develop a cytomegalovirus (CMV) infection while receiving bispecific antibody treatment. The goal is to see if maribavir can safely lower CMV levels in the blood. Participants will take maribav…

This study looks at whether people with gout who have kept their uric acid levels low for at least 5 years can safely take a lower dose or even stop their medication without symptoms coming back. About 59 adults will be split into three groups: one that reduces their febuxostat d…

This study tests whether bortezomib, a drug used for certain cancers, can safely raise platelet counts in adults with immune thrombocytopenia (ITP) that has come back or not responded to standard treatments. About 29 participants will receive the drug, and researchers will check …

This study tests whether the antiviral drug letermovir can prevent serious CMV infections in people with relapsed/refractory multiple myeloma who are being treated with elranatamab. About 40 adult participants who have had CMV in the past will receive letermovir alongside their c…

This study tests a personalized approach to managing fluids during brain surgery in children with Moyamoya disease, a rare condition where key brain arteries narrow. Instead of standard blood pressure monitoring, doctors will use each child's baseline heart function to guide flui…

This study compares two catheter ablation approaches for people with persistent atrial fibrillation (AF), a type of irregular heartbeat. The standard method isolates the pulmonary veins, while the experimental method also targets scarred areas in the left atrium. The goal is to s…

This study tests whether adding trastuzumab (a targeted therapy) to eribulin (a chemotherapy drug) works better than eribulin alone for people with advanced HER2-positive breast cancer that has not responded to at least two prior treatments. About 180 adults with metastatic or in…

This study is testing whether a radiation treatment for large liver tumors (over 5 cm) can be safely done in a single day. Normally, this treatment requires multiple visits. The researchers will enroll 138 patients with liver cancer who meet specific health criteria. The goal is …

This study tests a new microwave device to treat small liver cancers (up to 4 cm). Doctors will use imaging to guide a needle into the tumor and heat it to destroy the cancer cells. The goal is to see if the treatment can completely cover the tumor with a safety margin and preven…

This study tests a new treatment using stem cells from donated umbilical cords for people with rotator cuff disease—a common cause of shoulder pain. The goal is to see if it is safe and can reduce pain and improve shoulder function. About 21 adults who have not gotten better with…

This study tests a 12-week remote cardiac rehabilitation program for children aged 8 to 18 with complex congenital heart disease. Participants do exercises at home using apps or video platforms, guided by a team. The goal is to see if this program improves their exercise capacity…

This study tests whether a combination of two drugs, venetoclax and decitabine, can help adults with T-cell acute lymphoblastic leukemia or lymphoma that has come back or not responded to standard treatment. About 28 participants aged 19 to 79 will receive this modified chemother…

This study tests whether women with breast cancer who have no signs of cancer in their armpit lymph nodes after chemotherapy can safely skip armpit surgery. Half the participants will have standard sentinel node surgery; the other half will have no armpit surgery at all. Research…

This study tests a faster, simpler way to treat small liver cancers (up to 5 cm) using tiny radioactive beads. Normally, doctors do a special scan first to check where the beads go, but this study skips that step for certain patients. The goal is to see if the new approach is sti…

This study compares two approaches for people with a weak heart caused by blocked arteries: a procedure to open blockages (PCI) plus medication versus medication alone. Researchers want to see which better helps the heart pump blood. About 158 adults with low heart function and m…

This study looks at two approaches to blood thinners after a common heart procedure for atrial fibrillation. One group takes blood thinners every day as usual, while the other takes them only when a small implanted monitor detects the heart rhythm problem returning. The goal is t…

This study is testing a new ultrasound technique called DeepUSFF to see how well it measures liver fat compared to the current gold standard, MRI. About 62 adults with suspected fatty liver disease will get both scans. If successful, this could offer a faster, cheaper, and more a…

This study tests whether the blood thinner clopidogrel can prevent major heart problems like heart attacks and strokes in people who have early signs of artery disease on scans but don't yet need surgery. About 11,000 adults aged 40 and older with non-critical blockages will take…

This study tests if a special numbing injection (nerve block) can reduce pain and the need for strong painkillers after ear surgery in teenagers aged 13 to 18. Half of the 60 participants will get the injection before surgery, and the other half will not. The main goal is to see …

This study compares two pain medicines, sufentanil and remifentanil, given during brain bypass surgery. The goal is to see which one better prevents low blood pressure, a common complication. About 92 adults having planned brain bypass surgery will take part.

This study tests whether using a lower suction setting on a chest drainage device after lung cancer surgery can shorten the time a chest tube stays in. About 160 adults having lung surgery will be randomly assigned to either the standard suction or a gentler one. The goal is to s…

This study tests whether a special compression vest (called HUGgy) can reduce agitation in children aged 3 to 10 after tonsil and adenoid surgery. Half the children will wear the vest during recovery, while the other half receive standard care. Researchers will measure agitation …

This study tests whether a special recovery plan (ERAS) helps people leave the hospital sooner after minimally invasive stomach cancer surgery. About 308 adults will be randomly assigned to either the ERAS plan or standard care. The goal is to see if more patients meet discharge …

This study tests a comprehensive swallowing rehabilitation program for people with multiple system atrophy (MSA) who have trouble swallowing. Researchers want to see if the therapy can reduce the risk of food or liquid entering the airway and improve quality of life. The study wi…

This study is testing a special fabric shoulder brace that mimics muscle action to help people with neuromuscular disorders (like muscular dystrophy or ALS) move their arms better. About 30 participants will be evaluated with and without the brace to see if it improves reach, str…

This study looks at two methods of giving the sedative remimazolam during brain bypass surgery in people with Moyamoya disease. The goal is to see which method uses less total medicine. About 58 adults having this surgery will take part, and the results will help guide safer anes…

This study follows 1,000 adults in Korea who have symptoms of sleep apnea, like loud snoring or daytime sleepiness. Researchers will track how well patients stick with breathing machine therapy and monitor their health over time. The goal is to learn more about sleep apnea in thi…

This study watches 80 adults having airway surgery under general anesthesia with a special oxygen technique called THRIVE. Researchers record when oxygen levels fall below 92% and extra breathing help is needed. The goal is to find out which patients or factors predict this drop,…

This study compares a new AI-ultrasound device (AIIV L2) to standard manual blood draws. About 190 adults will get a blood draw on each arm—one with the device, one without—to see which is more successful on the first try, causes less pain, and takes less time. The goal is to fin…

This study compares a mixed reality (MR) CPR training system called HEROS 4.0 to standard instructor-led classes. 120 adults aged 18-50 who haven't had CPR training in the last year will participate. The goal is to see if MR training is as effective as traditional methods for lea…

This study watches how drug-coated balloons change blood flow and plaque in heart arteries. About 165 adults with coronary artery disease will get CT scans before and after the procedure. The goal is to see how these changes relate to patient outcomes.

This study enrolls 5,340 adults aged 19-79 who have experienced a cardiac arrest outside the hospital. Researchers aim to identify causes and risk factors by analyzing health behaviors, chronic diseases, and blood samples. The goal is to build a prediction model and discover new …

This study aims to learn more about near-death experiences (NDEs) by interviewing 200 adult patients who survived life-threatening events in the hospital, such as cardiac arrest or coma. Researchers will ask about their memories and feelings during those critical moments. The goa…

This study follows 40 Korean adults with blood cancers who receive a transplant of two umbilical cord blood units from unrelated donors. The goal is to see how well patients survive and recover, and to track side effects like graft-versus-host disease. No new treatment is being t…

This study watches 40 adults with atrial fibrillation who get a new heart procedure called pulsed field ablation. The goal is to see if tiny, symptomless spots appear on brain scans afterward. Researchers want to learn how safe this new technique is for the brain.

This study involves 30 adults with liver tumors who are scheduled for radioembolization, a treatment that delivers radiation directly to the tumor via tiny beads. Doctors currently use a test with a different particle (MAA) to see if the treatment might harm the lungs, but this t…

This study looks at two different veins (basilic and cephalic) for placing a midline catheter in children aged 2 to 17 who need one during surgery. The goal is to see which vein allows easier blood draws and causes fewer problems. About 96 children will take part, and the results…

This study is for people with advanced HER2-positive breast cancer whose current treatment (trastuzumab deruxtecan) has stopped working. Researchers want to see if switching immediately to another targeted drug (trastuzumab emtansine) can help control the cancer longer. About 100…

This study aims to find out if choosing the left or right nostril for inserting a breathing tube affects the chance of a nosebleed. About 208 adults having planned surgery will take part. Doctors will compare nosebleed rates between the two nostrils to see if one side is safer.