Seoul National University Hospital

This study tests two different intravenous fluids given during heart surgery to see which one better prevents serious kidney problems, death, or the need for dialysis afterward. About 1,292 adults having heart surgery will be randomly assigned to receive either hydroxyethyl starc…

This study looks at whether opening blocked heart arteries with a procedure (PCI) plus medications is better than medications alone for people with chronic coronary syndrome. About 2,300 adults aged 40 and older with confirmed blockages will be randomly assigned to one of the two…

This early-phase trial tests a combination of three drugs (golcadomide, poseltinib, and rituximab) in 20 adults with relapsed or refractory large B-cell lymphoma. The goal is to see if the combination can shrink or eliminate tumors. Participants must have tried other treatments f…

This study checks the long-term safety and effectiveness of a one-time stem cell treatment for rotator cuff disease. It follows 21 people who already received umbilical cord stem cells in an earlier trial. Researchers will measure shoulder pain and function over time using standa…

This early-phase study tests a method called PIPAC, which delivers chemotherapy as a pressurized spray directly into the abdomen. It is for women with ovarian cancer that has come back and is no longer responding to standard treatments. The goal is to find a safe dose and see if …

This study compares two methods for slowly reducing long-term low-dose steroids in people with rheumatoid arthritis (RA). About 206 adults with stable RA will be randomly assigned to either a split-dose or a 1 mg-by-1 mg tapering schedule, with some continuing their current dose …

This study tests a new combination of three drugs (nemtabrutinib, bortezomib, and rituximab) in people newly diagnosed with Waldenstrom's macroglobulinemia, a rare blood cancer. The goal is to see how well the treatment shrinks or controls the cancer. About 19 adults will take pa…

This study compares two surgical approaches for early-stage cervical cancer (IB2-IIA1): traditional open surgery and a newer minimally invasive method that uses a special stapler to prevent cancer cells from spreading. About 494 participants will be randomly assigned to one of th…

This study looks at whether removing the kidney tumor before or after immunotherapy works better for people with advanced kidney cancer that has spread. About 172 adults will be randomly assigned to have surgery first then immunotherapy, or immunotherapy first then surgery. Resea…

This study tests a special pacing method called Bachmann bundle pacing in 120 adults with heart failure and reduced pumping ability who already need an implantable defibrillator. The goal is to see if this pacing improves heart function and quality of life over 12 months. Partici…

This study compares an AI-enhanced electrocardiogram (ECG) to the standard heart ultrasound (echocardiogram) for managing atrial fibrillation. About 1,700 adults with AF and a moderate-to-high stroke risk will be randomly assigned to either AI-ECG-guided care or usual care with e…

This study tests whether a single dose of the steroid dexamethasone, given during nasal surgery, can improve sleep quality on the first night after the operation. About 100 adults having nasal surgery under general anesthesia will be randomly assigned to receive either dexamethas…

This study tests whether a newer anesthesia drug (remimazolam) followed by a reversal agent (flumazenil) causes less confusion and agitation when waking up from nasal surgery compared to a standard drug (propofol). About 204 adults will be randomly assigned to one of the two meth…

This study tests whether people with Parkinson's disease can safely and effectively follow a home exercise program using video instructions. Fifteen participants will exercise at home while a camera monitors their movements and gives real-time feedback. Researchers will check how…

This study explores whether a 12-week music therapy program can improve how children and teens (ages 10–19) with cochlear implants perceive melodies and enjoy music. About 25 participants will use a smartphone app for therapy and be tested before, during, and after the program. T…

This early-stage study tests a new way to deliver medication directly into the ear for people with hearing loss that hasn't improved with standard treatments. About 26 adults with sudden, Meniere's, or noise-induced hearing loss will receive the injection. Researchers will check …

This study looks for the smallest amount of IV fluid that can prevent low blood pressure during a C-section when given with a standard medicine. It will include 45 healthy pregnant women having planned C-sections. The fluid amount will be adjusted for each new participant based o…

This study tests whether playing binaural beats (a type of sound) through earphones during breast reconstruction surgery can lower the dose of the anesthetic drug remimazolam needed. 88 adults will be randomly assigned to either binaural beats or silent earphones. The goal is to …

This study looks at two different ultrasound machines to see if they can accurately measure liver stiffness and inflammation in people with fatty liver disease. About 95 to 100 adults will take part, including some healthy volunteers. The goal is to find a non-invasive way to tel…

This study will test how accurately the Dexcom G7 continuous glucose monitor measures blood sugar in 100 adults undergoing heart surgery. Researchers will compare the device's readings to standard lab tests. The goal is to see if this wearable sensor can be trusted during major s…

This study will collect information from 520 adults aged 65 and older before they have major non-heart surgery. Researchers will measure physical activity, nutrition, mood, body composition, and physical function. The goal is to build a model that can predict who is at higher ris…

This study will compare two types of video laryngoscope blades (hyperangulated vs. Macintosh) to see which one helps doctors place a breathing tube more successfully on the first try in adults having surgery with general anesthesia. About 524 participants will be randomly assigne…

This study looks at whether immune cells found in lung fluid can give doctors extra information about how well a lung cancer patient might respond to treatment. Researchers will collect samples from 60 adults with advanced lung cancer during a routine bronchoscopy. The goal is to…

This study explores why some people with a chronic lung infection called NTM-PD get worse while others stay stable. Researchers will analyze immune cells from the lungs and blood, along with nutrition and body composition, in 50 adults. The goal is to find better ways to predict …