Could a simple steroid injection replace a catheter for shoulder surgery pain?
NCT ID NCT07699744
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
Shoulder surgery often causes severe pain, and a nerve block is commonly used to numb the area. However, when the block wears off, many patients experience sudden intense 'rebound pain.' This trial tests whether a single-shot nerve block combined with an intravenous dose of the steroid dexamethasone can prevent rebound pain as effectively as a continuous nerve block that uses a catheter. The study involves 92 adults scheduled for shoulder surgery, and the main goal is to compare rebound pain scores in the first 24 hours after the block.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Dexamethasone (intravenous) plus single-shot nerve block
- What this could lead to
- If successful, this simpler approach could reduce rebound pain after shoulder surgery while avoiding the hassle and risks of a catheter-based continuous nerve block.
- What could go wrong
- This is a small Phase 4 trial with 92 participants, so results may not apply to all patients. The single-shot method might still lead to more rebound pain than the continuous block.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 92 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 79 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 19 to 79 years scheduled for elective shoulder surgery under brachial plexus block and monitored anesthesia care (MAC) Exclusion Criteria: * Pre-existing neurological deficit of the brachial plexus * Emergency surgery * American Society of Anesthesiologists (ASA) physical status classification IV or higher * Contraindication or history of hypersensitivity to local anesthetics or dexamethasone * Severe pulmonary disease (e.g., chronic obstructive pulmonary disease) * Body mass index (BMI) ≥ 35 kg/m² * Long-term use of steroids * Long-term use of analgesics * Inability to cooperate or communicate * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Seoul National University Hospital
Seoul, Jongno-gu, 03080, South Korea
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