Can a common drug curb Self-Harm? new trial aims to find out

NCT ID NCT07641283

Not yet recruiting Disease control Sponsor: Seoul National University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether naltrexone, a drug already used for addiction, can help people who hurt themselves without intending suicide. About 150 people will receive either naltrexone or a placebo daily for 6 weeks, alongside their usual care. Researchers will track how many self-injury episodes occur and whether urges decrease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: naltrexone
What this could lead to: If it works, this could point toward a medication to help reduce urges and episodes of self-injury.
What could go wrong: This is a small, early-stage trial with only 6 weeks of treatment. The drug may not reduce self-injury more than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Impulsive Behavior Self-Injurious Behavior Suicidal Ideation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NONSUICIDAL SELF-INJURY SELF-INJURIOUS BEHAVIOR

Contacts and locations

Locations

Asan medical center

Seoul, Songpa-gu, 05505, South Korea
Seoul National University Hospital

Seoul, Jongno-gu, 03080, South Korea
Uijeongbu Eulji Medical Center

Uijeongbu-si, Gyeonggi-do, 11759, South Korea

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