Seoul National University Hospital

This study tested whether dexmedetomidine, a sedative that preserves breathing better than other drugs, can protect the heart during cardiac bypass surgery. Researchers measured heart damage in 224 adults undergoing heart surgery with a heart-lung machine. The goal was to see if …

This study looked at 1,819 patients aged 60 or older with end-stage kidney disease. It compared those who received a living donor kidney transplant that was not a perfect match (ABO- or HLA-incompatible) to those who stayed on the waiting list or got a deceased donor kidney. The …

This study tested whether adding the immunotherapy drug pembrolizumab after standard chemoradiation helps control advanced nasopharyngeal cancer. Fifty-three patients received up to 17 cycles (about 1 year) of pembrolizumab. The main goal was to see how many patients remained can…

This study tested two different drug-coated stents (Everolimus vs. Sirolimus) in over 1,400 people with narrowed heart arteries. It also looked at whether taking a blood thinner for 6 months is as safe and effective as taking it for 12 months after getting a stent. The goal was t…

This study tested whether a low dose (10 mg) of the statin drug rosuvastatin works well in Korean adults who need cholesterol-lowering therapy. It included 242 people with high cholesterol, diabetes, or prior heart problems. The main goal was to see how much their LDL (bad) chole…

This study looked at how well the shingles vaccine works and how safe it is for people living with HIV. Researchers compared the immune response based on participants' CD4+ T-cell counts and age. The goal was to provide better guidance for vaccinating this group against shingles.

This study tested a new way to treat small liver cancer using microwave ablation with two antennas at once, instead of the usual single antenna. Twenty adults with early-stage liver cancer took part. The goal was to see if the two-antenna method could completely destroy the tumor…

This study looked at over 3,000 people with blocked heart arteries to compare two types of drug-coated stents (tiny mesh tubes that prop open arteries). One stent uses everolimus and the other uses sirolimus. The goal was to see which one is safer and works better over time in ev…

This study looked at over 3,400 people who had a heart attack or unstable angina and needed a stent to open blocked heart arteries. Researchers compared two types of stents (one with a permanent coating, one with a coating that dissolves) and two doses of the blood thinner prasug…

This study tested an improved radiofrequency ablation (heat treatment) method for liver cancer that came back after a prior procedure. One hundred adults with recurrent tumors received the treatment, and researchers tracked how many had tumor regrowth at the treated spot over two…

This study tested a combination of the immunotherapy drug durvalumab with two chemotherapy drugs (doxorubicin and ifosfamide) in 16 people with a rare and aggressive type of lung cancer called pulmonary sarcomatoid carcinoma. The goal was to see if the combo could shrink tumors a…

This study tested a combination of two drugs, bendamustine and rituximab, in 27 adults whose marginal zone B-cell lymphoma had come back or worsened after prior treatment. The goal was to see how many patients' tumors shrank or disappeared. The approach uses established chemother…

This study collected voice recordings and sensor data from 259 adults with swallowing difficulties. Researchers compared voice changes before and after meals with standard swallow tests to see if voice analysis alone could accurately detect problems like food going into the airwa…

This study looked at 40 children aged 7 to 17 who had bone graft surgery to fix a cleft in the gum. Doctors compared two ultrasound-guided pain blocks to see which one worked better. The goal was to find the best way to reduce pain and the need for strong pain medicine after surg…

This study tested a safe, self-administered brain stimulation technique called transcranial direct current stimulation (tDCS) in 24 people with Parkinson's disease. The goal was to see if it could improve walking, both normally and while doing another task at the same time. Parti…

This study tested whether a virtual reality (VR) experience can help workers recover from stress more quickly. Sixty healthy adults were put under stress and then randomly assigned to either a VR relaxation session or a control condition. Researchers measured stress by checking c…

This study tested whether low-dose radiation therapy can safely reduce pain and improve knee function in people with knee osteoarthritis. 114 adults aged 50-85 with moderate knee arthritis took part. The goal was to see if this treatment offers a new way to manage symptoms withou…

This study tested a wearable ear device that sends gentle electrical pulses to a nerve to help control appetite. Sixty healthy adult women each had two visits: one with the device on and one with it off. Researchers measured how much they ate, their hunger levels, and food cravin…

This study looked at whether giving a combination of acetaminophen and ibuprofen before surgery (preemptive) reduces the need for strong opioid painkillers after robot-assisted prostate removal compared to giving it after surgery starts (preventive). 154 men having prostate surge…

This study looked at 110 obese patients having knee or hip replacement surgery under spinal anesthesia. Researchers compared two ways to calculate the dose of a sedative called remimazolam: one based on ideal body weight and one on total body weight. The goal was to find which do…

This study looked at 201 children aged 3 to 18 having strabismus (crossed eyes) surgery. Researchers tested whether giving a deeper level of muscle relaxant during anesthesia could reduce a common side effect called the oculocardiac reflex, which causes a sudden drop in heart rat…

This study tested whether a cream made from icariin, a plant extract, can improve acne and reduce acne scars. Twenty-five adults applied the cream to one side of their face and a control solution to the other side twice daily for two months. The goal was to see if icariin reduces…

This study looked at whether amlodipine, a blood pressure medicine, can help people with coronary artery disease who have stents but still have narrow arteries. Over 200 participants took amlodipine or no calcium channel blocker for 9 months. The main goal was to see if exercise …

This study tested whether playing virtual reality exercise games could help people who had a stroke more than 6 months ago improve arm and hand movement. 15 chronic stroke patients with arm weakness participated. They used a VR headset to play specially designed games. The goal w…

This study tested whether using a smart watch and a phone app could help people with obstructive sleep apnea use their CPAP breathing machine more consistently. 46 adults who had trouble sticking with CPAP therapy were randomly assigned to use the smart watch and app or not. The …

This study looked at 77 never-smokers newly diagnosed with lung cancer to see how many also have sleep apnea and whether sleep apnea affects their cancer outlook. Participants had a sleep test before starting cancer treatment. The goal is to understand if sleep apnea is linked to…

This study looked at 241 kidney transplant patients to see how certain antibodies (AT1R-Ab) change before and after transplant. Researchers measured antibody levels over one year to understand their impact on kidney function and graft survival. The goal is to help doctors better …

This study tracked 48 children under 18 who received a midline catheter during surgery. Researchers monitored for complications like infection, blood clots, and blockages. They found that factors such as age, weight, and vein size can raise the risk. The goal is to make these cat…

This study looked at 258 adults having non-cardiac surgery to see if checking blood pressure every minute with a standard arm cuff works as well as using a continuous artery line to prevent low blood pressure during anesthesia start. The goal was to find out if the simpler, less …

This study explored whether a nutritional index (PNI) can predict death and other complications after brain tumor surgery. Researchers analyzed data from over 3,200 adults who had brain tumor surgery at a major hospital in South Korea. The goal was to see if this simple blood-bas…

This study observed 43 patients with stable coronary artery disease who had balloon angioplasty to open blocked heart arteries. Researchers measured blood flow after the procedure to see how it related to X-ray images of the arteries. They also compared two types of balloons (sco…

This study looked at how brain activity (measured by EEG) changes when a breathing tube is placed and when a surgical cut is made during abdominal surgery. Researchers measured stress hormones at the same time to see if they are linked. 52 adults having open abdominal surgery too…

This study looked at over 17,000 people with coronary artery disease who received drug-eluting stents (small mesh tubes coated with medicine) to open blocked heart arteries. The goal was to compare different types of stents and track how well they worked and how safe they were ov…

This study looked at 337 adults having laparoscopic surgery to see if the pressure in their breathing tube during the operation affected whether they got a sore throat afterward. The researchers measured how long the tube pressure was too high and checked for sore throat 1 hour a…