New needle combo zaps returning liver tumors after failed chemo

NCT ID NCT07192172

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a special type of radiofrequency ablation using two cooled needles that also release saline to treat liver cancer that came back after chemoembolization. The goal was to see if this technique could better destroy the tumor and prevent it from growing back. One hundred adults with recurrent liver cancer were treated, and researchers tracked how many had tumor regrowth at the treatment site over two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Twin Internally Cooled-Perfusion (TICP) electrodes for bipolar radiofrequency ablation

What this could lead to

If successful, this technique could offer a more effective way to destroy recurrent liver tumors after initial treatment, potentially improving local control and survival.

What could go wrong

This is a single-center, non-randomized study with only 100 participants. The results may not apply to all patients, and the procedure carries risks like bleeding or damage to nearby structures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver and intrahepatic bile duct neoplasm Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Hosptial

    Seoul, Seoul, 03080, South Korea