Seoul National University Hospital

This pilot study aimed to test whether a mixture of dexamethasone, hyaluronic acid, and a green dye could be safely injected into the ear to treat certain types of hearing loss that don't improve with standard treatments. The plan was to enroll 26 adults with sudden hearing loss,…

This phase 2 trial tests a combination of two drugs, tislelizumab and pemetrexed, in 28 adults with a rare type of brain lymphoma (primary DLBCL of the CNS) that has relapsed or not responded to standard treatment. The goal is to see if the combination can shrink tumors and impro…

This study tests a special electrode for radiofrequency ablation in people with small liver cancers (3 cm or less). The electrode monitors temperature and can adjust its tip to match tumor shape, aiming to destroy the tumor while protecting nearby organs. Researchers will track w…

This study looks at how well a treatment called 90Y radioembolization works for people with early-stage liver cancer. Researchers will track 200 patients in Korea to see how the tumors respond, how long patients live, and any side effects. The goal is to gather real-world data to…

This study tests a new fluorescent clip that glows under special light to help surgeons locate colon tumors during minimally invasive surgery. About 110 adults with colon cancer will be randomly assigned to receive either the clip or a standard dye injection before surgery. The g…

This study tests fecal microbiota transplantation (FMT) in 30 people with mild-to-moderate ulcerative colitis. Participants receive donor stool either through a colonoscopy or as capsules at weeks 0 and 4. The goal is to see if FMT can help achieve steroid-free remission and impr…

This study aims to find the smallest effective dose of the numbing drug ropivacaine for blocking leg nerves during diabetic foot surgery. Researchers will test different concentrations in 45 adults to see which dose works best for 90% of patients. The goal is to provide effective…

This study measures how well the brain controls its own blood flow in preterm and full-term infants during non-cardiac surgery. Using a special light-based monitor on the forehead, researchers track oxygen levels in the brain and compare them to blood pressure. The goal is to ide…

This study follows 640 adults with normal cognition, mild cognitive impairment, or Alzheimer's disease to track brain changes over time. Researchers use advanced brain scans and genetic tests to understand how Alzheimer's develops. The goal is to find better ways to diagnose and …

This study tests whether virtual reality (VR) can train new doctors as well as high-fidelity mannequins for handling emergencies like severe allergic reactions and low oxygen levels. 124 medical interns will be randomly assigned to either VR or mannequin training, then tested on …

This study planned to use a gentle brain stimulation technique called tDCS to see if it could help people with schizophrenia who have negative symptoms (like lack of motivation or emotion). Researchers wanted to use brain scans to understand how it works. However, the study was w…

This study looks at why some lung cancers stop responding to the drug osimertinib. Researchers will analyze the genetic makeup of tumors from 148 patients with advanced EGFR-mutant lung cancer who take osimertinib as their first treatment. The goal is to identify resistance mecha…

This study looks at whether women with small breast cancers (under 5 cm) and no signs of cancer in their lymph nodes on ultrasound can safely skip sentinel lymph node biopsy during breast-conserving surgery. About 1,734 women are being randomly assigned to either have the biopsy …

This study compares two devices—a videolaryngoscope and a flexible bronchoscope—for placing a breathing tube through the nose during ear, nose, and throat surgery. Researchers will measure which device succeeds on the first try more often, and track side effects like sore throat …

This study looks at how the tumor microenvironment changes during chemotherapy in 30 patients with HER2-positive breast cancer. Researchers will take samples before, during, and after treatment to see what happens at the cellular level. The goal is to better understand how chemot…

This study looks at whether having low muscle mass (sarcopenia) before lung cancer surgery affects how well patients recover. Researchers will follow 400 older adults having lung cancer surgery to see if sarcopenia is linked to survival and other outcomes. The goal is to find out…

This study looks at how the 'watch and wait' approach affects the quality of life of people with slow-growing lymphomas like CLL and follicular lymphoma. Researchers will ask 250 Korean patients to fill out questionnaires about their well-being and anxiety. The goal is to underst…

This study is testing whether a video-based, parent-led developmental training program is feasible for preterm infants with brain injury. Twelve families will use a video platform (Zoom) for twice-weekly sessions at home, guided remotely by a therapist. The goal is to see if pare…

This study is collecting health information from 2,000 people with Crohn's disease or ulcerative colitis across three hospitals in South Korea. Researchers aim to build computer models that can predict how each patient will respond to different treatments. No new drugs are being …