Inside the tumor: scientists track Chemo's impact on breast cancer microenvironment

NCT ID NCT06533670

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the tumor microenvironment changes during chemotherapy in 30 patients with HER2-positive breast cancer. Researchers will take samples before, during, and after treatment to see what happens at the cellular level. The goal is to better understand how chemotherapy works and why some tumors respond better than others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand why some HER2-positive breast cancers respond better to chemotherapy, potentially guiding more personalized treatment.
What could go wrong
This is a small, observational study with only 30 participants, so results may not apply to all patients. It is not testing a new treatment, so direct patient benefits are limited.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Hospital

    Seoul, South Korea

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Other studies related to the condition(s) this trial covers.