Scientists pinpoint ideal painkiller dose for diabetic foot operations

NCT ID NCT04981067

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to find the smallest effective dose of the numbing drug ropivacaine for blocking leg nerves during diabetic foot surgery. Researchers will test different concentrations in 45 adults to see which dose works best for 90% of patients. The goal is to provide effective pain relief while using the lowest possible amount of medicine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ropivacaine

What this could lead to

If successful, this could help doctors use the right amount of numbing medicine for diabetic foot surgery, reducing pain and risks.

What could go wrong

This is a small, early-phase study with only 45 people. The results may not apply to everyone, and the best dose might still cause side effects or fail to numb properly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot diabetic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Hospital

    Seoul, 03080, South Korea