Pig liver scaffold may speed healing of stubborn diabetic wounds

NCT ID NCT07632001

Recruiting now Disease control Sponsor: Reprise Biomedical, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests whether a special scaffold made from pig liver tissue, called Miro3D, can help heal chronic diabetic foot ulcers when added to standard wound care. About 180 adults with non-healing ulcers will be randomly assigned to receive either Miro3D plus standard care or standard care alone. The main goal is to see if Miro3D leads to more wounds closing completely within 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Miro3D Wound Matrix (a scaffold made from pig liver tissue)
What this could lead to: If it works, this could offer a new option to help heal stubborn diabetic foot ulcers and reduce the risk of complications like infection or amputation.
What could go wrong: This is a relatively early-stage trial with 180 participants, so results may not apply to everyone. The scaffold is from animal tissue, which could cause allergic reactions or rejection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC WOUNDS DIABETIC FOOT DIABETIC FOOT ULCERS (DFUS)

Contacts and locations

Locations

ABC Podiatry
RECRUITING

Columbus, Ohio, 43213, United States
Advanced Foot Care
RECRUITING

Phoenix, Arizona, 85032, United States
Barry University
RECRUITING

Tamarac, Florida, 33321, United States
Caring Foot and Ankle Specialists
RECRUITING

Houston, Texas, 77035, United States
Christian Hospital Wound Center
NOT_YET_RECRUITING

St Louis, Missouri, 63136, United States
Clinical Trials of New England
NOT_YET_RECRUITING

Hyde Park, Massachusetts, 02136, United States
Doctors Research Network
NOT_YET_RECRUITING

Miami, Florida, 33156, United States
Dynamic Wound Care
NOT_YET_RECRUITING

Oklahoma City, Oklahoma, 73159, United States
Icahn School of Medicine at Mount Sinai
NOT_YET_RECRUITING

New York, New York, 10029, United States
Mercy Hyperbaric and Wound Care
NOT_YET_RECRUITING

St Louis, Missouri, 63128, United States
Solutions Medical Research
RECRUITING

Coral Gables, Florida, 33134, United States
St. Louis Foot & Ankle
NOT_YET_RECRUITING

St Louis, Missouri, 63128, United States
Vital Heart and Vein
RECRUITING

Humble, Texas, 77338, United States
West Boca Center for Wound Healing
NOT_YET_RECRUITING

Coconut Creek, Florida, 33073, United States

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