Placenta power: could donor cells heal diabetic foot wounds?

NCT ID NCT02264288

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injections of cells from donated human placentas can help heal foot ulcers in people with diabetes. The trial includes patients with and without peripheral artery disease, a common complication that slows healing. Participants receive either the cell treatment or a placebo, and researchers track wound closure over three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

human placenta-derived cells (PDA-002)

What this could lead to

If it works, this could offer a new way to heal stubborn diabetic foot ulcers, especially for those with poor blood flow.

What could go wrong

This is a mid-stage trial, so results are not yet proven. The treatment may not work better than placebo, and there could be unknown side effects from the cell injections.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 1Foot 2Foot Centre for Foot & Ankle Care PC

    Suffolk, Virginia, 23434, United States

  • Advanced Foot & Ankle Center

    Salt Lake City, Utah, 84102, United States

  • Animas Foot and Ankle

    Durango, Colorado, 81301, United States

  • Arizona Arthritis and Rheumatology Research, PLLC

    Phoenix, Arizona, 85023, United States

  • Bert J Altmanshofer and associates, LTD

    Duncansville, Pennsylvania, 16635, United States

  • CGH Medical Center Main Clinic

    Sterling, Illinois, 61081, United States

  • Cardiology PC

    Birmingham, Alabama, 35211, United States

  • Carilion Clinic

    Roanoke, Virginia, 24013, United States

  • Carl T. Hayden Veterans Affairs Medical Center

    Phoenix, Arizona, 85012, United States

  • Center for Clinical Research Inc.

    San Francisco, California, 94115, United States

  • Clinical Research of West Florida Inc - Clearwater

    Clearwater, Florida, 33765, United States

  • Endeavor Clinical Trials PA

    San Antonio, Texas, 78229, United States

  • Englewood Hospital and Medical Center

    Englewood, New Jersey, 07631, United States

  • Florida Research Network, LLC

    Gainesville, Florida, 32605, United States

  • Foot and Ankle Center of Illinois

    Springfield, Illinois, 62704, United States

  • Foot and Ankle Clinic

    Los Angeles, California, 90057, United States

  • Futuro Clinical trials

    McAllen, Texas, 78501-2930, United States

  • GF Professional Research Group Corporation

    Miami Lakes, Florida, 33016, United States

  • Georgetown University Medical Center Lombardi Cancer Center

    Washington D.C., District of Columbia, 20007-2197, United States

  • Hamilton Foot Care

    Baltimore, Maryland, 21214, United States

  • Jeffrey A Klemes DPM

    Beverly Hills, California, 90211, United States

  • Limb Preservation Platform, INC.

    Fresno, California, 93720, United States

  • Milwaukee Foot & Ankle Specialists

    Wauwatosa, Wisconsin, 53226, United States

  • NEA baptist clinic

    Jonesboro, Arkansas, 72401, United States

  • Northwest Hospital

    Randallstown, Maryland, 21133, United States

  • Ocean City Foot and Ankle Assoc

    Toms River, New Jersey, 08753, United States

  • Office of Michael J. De Marco, DPM

    Newark, New Jersey, 07102, United States

  • Podiatry 1st

    Belleville, Illinois, 62226, United States

  • Premier Vein and Vascular Center

    Houston, Texas, 77084, United States

  • Reliance Clinical Research

    Chino, California, 91710, United States

  • Revive Research Institute

    Sterling Heights, Michigan, 48313, United States

  • Rosalind Franklin University of Medicine and Science

    North Chicago, Illinois, 60064, United States

  • SAM Clinical Research Center

    San Antonio, Texas, 78229, United States

  • Sinai Hospital of Baltimore

    Baltimore, Maryland, 21215, United States

  • Solutions Through Advanced Research Inc.

    Jacksonville, Florida, 32258, United States

  • Stanford University

    Stanford, California, 94063, United States

  • Swagel wootoon hiatt eye center

    Mesa, Arizona, 85206, United States

  • The Research Center

    Hialeah, Florida, 33012, United States

  • UNC Hospitals University of North Carolina

    Chapel Hill, North Carolina, 27599-7010, United States

  • University of Florida

    Jacksonville, Florida, 32209, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Pennsylvania Health Systems

    Philadelphia, Pennsylvania, 19104, United States

  • VA Palo Alto Health Care System

    Palo Alto, California, 94304, United States

  • Weill Foot & Ankle Institute

    Des Plaines, Illinois, 60016, United States

  • Well Pharma Medical Research Corporation

    Miami, Florida, 33143, United States