Poop pills or scope: can donor stool tame ulcerative colitis?

NCT ID NCT07154784

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests fecal microbiota transplantation (FMT) in 30 people with mild-to-moderate ulcerative colitis. Participants receive donor stool either through a colonoscopy or as capsules at weeks 0 and 4. The goal is to see if FMT can help achieve steroid-free remission and improve symptoms over 48 weeks, while also checking for safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
fecal microbiota transplantation (FMT) – donor stool given via colonoscopy or capsules
What this could lead to
If it works, this could offer a way to control ulcerative colitis without long-term steroids, possibly reducing flare-ups and improving quality of life.
What could go wrong
This is a small, early-phase study with only 30 participants. The treatment may not work for everyone, and there are risks of infection or worsening symptoms from the transplant.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of Medicine

    Seoul, Dongjak-gu, 07061, South Korea

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