Breast cancer breakthrough: thousands may avoid unnecessary surgery

NCT ID NCT04303715

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether women with small breast cancers (under 5 cm) and no signs of cancer in their lymph nodes on ultrasound can safely skip sentinel lymph node biopsy during breast-conserving surgery. About 1,734 women are being randomly assigned to either have the biopsy or not, and researchers will track cancer recurrence and survival over time. The goal is to reduce unnecessary surgery and side effects without harming outcomes.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Hospital

    Seoul, Seoul, 03080, South Korea