SENTINEL LYMPH NODE

This study looks at whether radiation therapy to the underarm area is as effective as surgery to remove lymph nodes in breast cancer patients who still have cancer in their sentinel node after chemotherapy. The goal is to see if radiation causes less arm swelling (lymphedema) whi…

This study tests whether injecting a near-infrared dye near a lung tumor can help surgeons see the tumor and the first lymph node it drains to during surgery. About 100 adults having lung surgery will receive the dye, and doctors will check if it safely improves the removal of ca…

This study looks at whether women with early breast cancer that has spread to lymph nodes can safely avoid additional surgery or radiation to the armpit after chemotherapy, if tests show the cancer is gone from those nodes. The goal is to see if skipping extra treatment is just a…

This study is for people with early-stage colon cancer (stage I) who currently need a colectomy to remove part of the colon. The SENTRY trial tests a less invasive option: removing only the tumor and nearby lymph nodes using a camera and a special dye. The goal is to see if this …

This study tests if a safe green dye (indocyanine green) can help surgeons find cancer-spreading lymph nodes through the same cut used for mastectomy, avoiding a separate armpit incision. About 90 women with early breast cancer will receive the dye during surgery. The goal is to …

This study tests a special dye that makes cancer cells glow, helping surgeons quickly tell if a lymph node contains cancer during breast cancer surgery. About 60 adults with breast cancer will have their removed lymph nodes treated with the dye and then imaged. The goal is to see…

This study tests a new way to find the first lymph node where breast cancer might spread. Instead of using a radioactive tracer, doctors use a green dye and a special camera during surgery. The goal is to make the procedure safer, easier, and more available in hospitals across th…

This study looks at whether a less invasive procedure called sentinel node biopsy can help women with early-stage endometrial cancer recover faster and avoid side effects like leg swelling, compared to not removing any lymph nodes. About 760 women will be randomly assigned to one…

This study looks at whether special imaging can help find the first lymph nodes that cancer might spread to in women with inflammatory breast cancer. About 50 women will take part. The goal is to improve surgery and understand the risk of arm swelling after treatment.

This study looks at a less invasive technique called target axillary dissection (TAD) to check if cancer has spread to lymph nodes after chemotherapy in people with locally advanced breast cancer. The goal is to see if TAD is accurate enough to replace more extensive lymph node r…