SENTINEL LYMPH NODE

This study looks at women and men with early-stage breast cancer that had spread to lymph nodes. After chemotherapy, if a sentinel node biopsy shows no cancer left, the trial compares doing nothing further versus standard axillary lymph node removal or radiation. The goal is to s…

This study tests a less invasive surgery for people with early-stage colon cancer (stage I). Instead of removing a large section of the colon, doctors will remove only the tumor and a few nearby lymph nodes using a special dye. The goal is to see if this smaller surgery works as …

This study tests if a safe green dye (indocyanine green) can help surgeons find lymph nodes that might contain cancer during a mastectomy, without needing a separate cut under the arm. About 90 women with early-stage breast cancer will receive the dye and a standard radioactive t…

This study tests whether injecting a near-infrared dye called indocyanine green (ICG) around a lung tumor can help surgeons see the tumor and the first lymph node it drains to during surgery. About 100 adults having lung surgery will receive the dye, and a special camera will det…

This study tests a special dye that makes cancer cells glow when applied to lymph nodes removed during breast cancer surgery. The goal is to help surgeons instantly tell if a sentinel lymph node contains cancer, so they only remove the nodes that are truly affected. The trial wil…

This study compares two approaches for breast cancer patients who still have cancer in their sentinel lymph node after chemotherapy: removing the underarm lymph nodes (surgery) or treating them with radiation. The goal is to see if radiation can reduce the risk of arm swelling (l…

This study aims to help Dutch hospitals switch from using a radioactive tracer to a green dye called indocyanine green (ICG) to find the first lymph node that breast cancer may spread to. The dye is given during surgery, avoids radiation, and requires no extra hospital visits. Re…

This study looks at whether removing only a few key lymph nodes (sentinel node biopsy) is better than removing no nodes at all in women with early-stage endometrial cancer. The goal is to see if this approach helps women return to normal activities faster and does not increase th…

This study looks at whether special imaging and dye can help doctors find the first lymph nodes that cancer might spread to in people with inflammatory breast cancer. About 50 women with this rare and aggressive cancer will take part. The goal is to see if these methods work well…

This study is testing whether a less invasive procedure called target axillary dissection (TAD) can accurately check for cancer spread in the lymph nodes of people with locally advanced breast cancer after chemotherapy. The goal is to see if TAD can replace more extensive lymph n…