New study aims to spare breast cancer patients from extensive surgery

NCT ID NCT05763641

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether a less invasive procedure called target axillary dissection (TAD) can accurately check for cancer spread in the lymph nodes of people with locally advanced breast cancer after chemotherapy. The goal is to see if TAD can replace more extensive lymph node removal, which often causes long-term side effects like arm swelling. The study will enroll 162 participants and compare TAD results with standard full lymph node removal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could validate a less invasive surgical approach for advanced breast cancer, potentially reducing arm swelling and other complications.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve outcomes. The method may not be accurate enough to replace standard surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Clínico y Provincial de Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital de Bellvitge

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

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