Glow-in-the-Dark dye could spare breast cancer patients unnecessary surgery

NCT ID NCT07154563

Recruiting now Diagnosis Sponsor: Yunnan Cancer Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a special dye that makes cancer cells glow when applied to lymph nodes removed during breast cancer surgery. The goal is to help surgeons instantly tell if a sentinel lymph node contains cancer, so they only remove the nodes that are truly affected. The trial will enroll 60 adults with breast cancer and compare the dye's results with standard lab tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NIR-II fluorescent probe (ICG-CK)
What this could lead to: If successful, this could give surgeons a real-time tool to tell cancerous from healthy lymph nodes during surgery, potentially reducing side effects like arm swelling.
What could go wrong: This is an early-stage, small trial (60 people) testing a new imaging method. The dye may not reliably distinguish all cancer types, and false positives or negatives are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm metastatic neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER, METASTATIC METASTASIS SENTINEL LYMPH NODE SENTINEL LYMPH NODE BIOPSY (SLNB)

Contacts and locations

Locations

Yunnan Cancer Hospital, Kunming, Yunnan 650118
RECRUITING

Kunming, Yunnan, China

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