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New study aims to determine if less surgery is better for Early-Stage endometrial cancer

NCT ID NCT04073706

Recruiting now Knowledge-focused Sponsor: Queensland Centre for Gynaecological Cancer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether removing only a few key lymph nodes (sentinel node biopsy) is better than removing no nodes at all in women with early-stage endometrial cancer. The goal is to see if this approach helps women return to normal activities faster and does not increase the risk of cancer coming back. About 760 women will take part, and the results will help guide future treatment decisions.

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Conditions

The condition(s) this trial relates to.

endometrium neoplasm stage I endometrioid carcinoma uterine cancer uterine carcinosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER STAGE I SENTINEL LYMPH NODE SURGERY

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Azienda Sanitaria Universitaria Friuli Centrale (ASUFC)

    RECRUITING

    Udine, Via Pozzuolo, 33100, Italy

  • Buderim Private Hospital

    RECRUITING

    Buderim, Queensland, 4556, Australia

    Contact Email: •••••@•••••

  • Centro de tratamiento e investigación sobre Cáncer Luis Carlos Sarmiento Angulo

    RECRUITING

    Bogotá, Bogotá, Distrito Capital, 110131, Colombia

  • Chris O'Brien Lifehouse

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

  • Fundacao Antonio Prudente, AC Camargo Cancer Center

    RECRUITING

    São Paulo, São Paulo, Brazil

  • Gold Coast University Hospital

    NOT_YET_RECRUITING

    Southport, Queensland, 4215, Australia

    Contact Email: •••••@•••••

  • Hospital Britanico

    NOT_YET_RECRUITING

    Buenos Aires, Ciudad Autónoma de Buenos Aires (caba), Argentina

  • Hospital Israelita Albert Einstein

    NOT_YET_RECRUITING

    São Paulo, São Paulo, Brazil

  • Hospital de Base

    RECRUITING

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • Liverpool Hospital

    RECRUITING

    Liverpool, New South Wales, 2170, Australia

  • Mater Hospital

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact Email: •••••@•••••

  • Mercy Hospital for Women

    RECRUITING

    Heidelberg, Victoria, 3084, Australia

  • National University Hospital and National University Cancer Institute

    RECRUITING

    Singapore, NUH Zone B, 119074, Singapore

  • North West Private Hospital

    RECRUITING

    Everton Park, Queensland, 4053, Australia

    Contact Email: •••••@•••••

  • Royal Brisbane and Women's Hospital

    RECRUITING

    Herston, Queensland, 4029, Australia

    Contact Email: •••••@•••••

  • Royal Women's Hospital

    RECRUITING

    Parkville, Victoria, 3052, Australia

  • St Andrews War Memorial Hospital

    RECRUITING

    Spring Hill, Queensland, 4000, Australia

    Contact Email: •••••@•••••

  • The Wesley Hospital

    RECRUITING

    Auchenflower, Queensland, 4066, Australia

    Contact Email: •••••@•••••

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