Could Low-Dose radiation be the next knee pain fix?
NCT ID NCT05562271
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether low-dose radiation therapy can reduce pain and improve function in people with knee osteoarthritis. 114 adults aged 50-85 with moderate knee arthritis received either low-dose radiation or a sham treatment. Researchers measured pain and function improvements over 4 months to see if this approach is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low-dose radiation therapy
What this could lead to
If it works, this could offer a new, non-drug option for reducing knee pain and improving mobility in people with osteoarthritis.
What could go wrong
This is an early exploratory trial with only 114 participants. The benefits may be small or not last long, and radiation carries potential risks like tissue damage, though at low doses.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Samsung Medical Center
Seoul, South Korea
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Seoul National University Hospital
Seoul, South Korea
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Seoul National University Hospital / SMG-SNU Boramae Medical Center
Seoul, 07061, South Korea