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Heart stent showdown: does adding a procedure to pills prevent more heart attacks?

NCT ID NCT07577518

Not yet recruiting Disease control Sponsor: Seoul National University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two approaches for people with chronic coronary syndrome (narrowed heart arteries): getting a stent plus standard medications versus medications alone. About 2,301 participants will be randomly assigned to one group, and researchers will track major heart events like heart attacks or death. A smaller substudy will also test two forms of the drug carvedilol for angina control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
percutaneous coronary intervention (PCI) and carvedilol
What this could lead to
If successful, this could show that adding a stent procedure to standard medications reduces major heart events like heart attacks or death in people with chronic coronary syndrome.
What could go wrong
This trial hasn't started yet, and results may not show a clear benefit of PCI over medication alone. The carvedilol substudy is small (220 people), so findings may be limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC CORONARY SYNDROME

Contacts and locations

Locations

  • Bucheon Sejong Hospital

    Bucheon-si, Gyeonggi-do, 14754, South Korea

  • Chungnam National University Hospital

    Daejeon, 35015, South Korea

  • Chungnam National University Hospital

    Gwangju, 61469, South Korea

  • Ewha Womans University Medical Center

    Seoul, 07804, South Korea

  • GangNeung Asan Hospital

    Gangneung, Gangwon-do, 25440, South Korea

  • Hallym University Medical Center

    Anyang-si, Gyeonggi-do, 14068, South Korea

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Inje University Ilsan Paik Hospital

    Goyang-si, Gyeonggi-do, 10380, South Korea

  • Jeju National University Hospital

    Jeju City, 63241, South Korea

  • Kangdong Sacred Heart Hospital

    Seoul, 05355, South Korea

  • Kangwon National University Hospital

    Chuncheon, Gangwon-do, 24289, South Korea

  • Keimyung University Dongsan Hospital

    Daegu, 41931, South Korea

  • Koera University Guro Hospital

    Seoul, 08308, South Korea

  • Kosin University Gospel Hospital

    Busan, 49267, South Korea

  • Kyungpook National University Hospital

    Daegu, 41944, South Korea

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Samsung Changwon Medical Center

    Changwon, Gyeongsangnam-do, 51353, South Korea

  • Seoul Metropolitan Government Seoul National University Boramae Medical Center

    Seoul, 07061, South Korea

  • The Catholic University of Korea Daejeon St. Mary's Hospital

    Daejeon, 34943, South Korea

  • Ulsan Univeristy Hospital

    Ulsan, 44033, South Korea

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