Heart stent showdown: does adding a procedure to pills prevent more heart attacks?

NCT ID NCT07577518

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two approaches for people with chronic coronary syndrome (narrowed heart arteries): getting a stent plus standard medications versus medications alone. About 2,301 participants will be randomly assigned to one group, and researchers will track major heart events like heart attacks or death. A smaller substudy will also test two forms of the drug carvedilol for angina control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

percutaneous coronary intervention (PCI) and carvedilol

What this could lead to

If successful, this could show that adding a stent procedure to standard medications reduces major heart events like heart attacks or death in people with chronic coronary syndrome.

What could go wrong

This trial hasn't started yet, and results may not show a clear benefit of PCI over medication alone. The carvedilol substudy is small (220 people), so findings may be limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC CORONARY SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bucheon Sejong Hospital

    Bucheon-si, Gyeonggi-do, 14754, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chungnam National University Hospital

    Daejeon, 35015, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chungnam National University Hospital

    Gwangju, 61469, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ewha Womans University Medical Center

    Seoul, 07804, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GangNeung Asan Hospital

    Gangneung, Gangwon-do, 25440, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hallym University Medical Center

    Anyang-si, Gyeonggi-do, 14068, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inje University Ilsan Paik Hospital

    Goyang-si, Gyeonggi-do, 10380, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jeju National University Hospital

    Jeju City, 63241, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kangdong Sacred Heart Hospital

    Seoul, 05355, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kangwon National University Hospital

    Chuncheon, Gangwon-do, 24289, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Keimyung University Dongsan Hospital

    Daegu, 41931, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Koera University Guro Hospital

    Seoul, 08308, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kosin University Gospel Hospital

    Busan, 49267, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kyungpook National University Hospital

    Daegu, 41944, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pusan National University Hospital

    Busan, 49241, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Samsung Changwon Medical Center

    Changwon, Gyeongsangnam-do, 51353, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul Metropolitan Government Seoul National University Boramae Medical Center

    Seoul, 07061, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Catholic University of Korea Daejeon St. Mary's Hospital

    Daejeon, 34943, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ulsan Univeristy Hospital

    Ulsan, 44033, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••