Small study aims to perfect fluid dosing for safer C-Sections
NCT ID NCT07324512
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing different amounts of IV fluid given during spinal anesthesia for planned C-sections to find the smallest dose that prevents dangerously low blood pressure in 90% of women. 45 healthy pregnant women at term will receive a specific fluid volume right after the spinal injection, and the dose will be adjusted for each next participant based on results. The goal is to improve safety for both mother and baby without using more fluid than needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intravenous crystalloid fluid (balanced salt solution)
What this could lead to
If successful, this could establish a standard fluid dose to prevent dangerous drops in blood pressure during C-sections, making the procedure safer for mothers and newborns.
What could go wrong
This is a very small, early-phase dose-finding study (45 participants) with no comparison group. Results may not apply to all pregnant women, and the optimal dose may still fail in some cases.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.