Cancer drug could help patients with low platelet disorder

NCT ID NCT05599880

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests the drug bortezomib in 29 adults with relapsed or refractory immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, raising bleeding risk. Participants receive bortezomib injections over three weeks for three cycles, then are followed for a year. The goal is to see if the drug can safely raise platelet counts to safer levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bortezomib

What this could lead to

If successful, bortezomib could offer a new treatment option for people with immune thrombocytopenia that hasn't responded to other therapies.

What could go wrong

This is a small, early-phase trial with only 29 participants. It may not work for everyone, and bortezomib can cause side effects like nerve damage and low blood cell counts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune thrombocytopenic purpura Purpura, Thrombocytopenic, Idiopathic thrombocytopenia due to immune destruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • SMG-SNU Boramae Medical Center

    RECRUITING

    Seoul, 07061, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Bundang Hospital

    RECRUITING

    Guri-si, South Korea

    Contact

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

    Contact

  • Seoul National University Hospital

    NOT_YET_RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact