New scout dose method could make liver cancer radiation safer for lungs

NCT ID NCT07476651

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new method to check if a liver cancer treatment called radioembolization is safe for the lungs. Currently, doctors use a test particle (MAA) to estimate lung radiation risk, but it may not be perfectly accurate. The new method uses a small 'scout dose' of the actual treatment beads (Y-90 microspheres) and a PET/CT scan to get a more precise measurement. The study will enroll 30 adults with liver tumors to compare the two approaches.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Yttrium-90 resin microspheres (SIR-Spheres)
What this could lead to
If successful, this could make radioembolization safer by more accurately measuring how much radiation reaches the lungs, and provide a reliable alternative when the current test is unavailable.
What could go wrong
This is a small early study with only 30 participants, so results may not apply to everyone. The extra procedure adds time and discomfort, and the scout dose itself carries a small radiation risk.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

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