Can a reversal drug wake up ICU patients faster after a breathing tube?
NCT ID NCT05993390
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving a drug to reverse muscle relaxants after placing a breathing tube helps doctors check brain function sooner. Thirty critically ill adults in the ICU will receive either sugammadex, neostigmine, or no reversal drug. Researchers will measure how quickly patients can open their eyes or move on command.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sugammadex and neostigmine
- What this could lead to
- If it works, this could help doctors assess brain function faster in critically ill patients after intubation.
- What could go wrong
- This is a very small early-phase study with only 30 participants, so results may not apply broadly. The drugs themselves carry risks like allergic reactions or side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Seoul National University Hospital
RECRUITINGSeoul, Jongno-gu, 03080, South Korea
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