Can a reversal drug wake up ICU patients faster after a breathing tube?
NCT ID NCT05993390
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving a drug to reverse muscle relaxants after placing a breathing tube helps doctors check brain function sooner. Thirty critically ill adults in the ICU will receive either sugammadex, neostigmine, or no reversal drug. Researchers will measure how quickly patients can open their eyes or move on command.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sugammadex and neostigmine
What this could lead to
If it works, this could help doctors assess brain function faster in critically ill patients after intubation.
What could go wrong
This is a very small early-phase study with only 30 participants, so results may not apply broadly. The drugs themselves carry risks like allergic reactions or side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Seoul National University Hospital
RECRUITINGSeoul, Jongno-gu, 03080, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••