NEUROMUSCULAR BLOCKADE

This study tests a new drug, HRS-9190, against a standard muscle relaxant used during surgery. About 60 adults having planned surgery will get one of the two drugs. The main goal is to see how fast muscles recover after the drug is stopped. Researchers will also check for side ef…

This study tests whether giving a drug to reverse muscle relaxants after placing a breathing tube helps doctors check brain function sooner. Thirty critically ill adults in the ICU will receive either sugammadex, neostigmine, or no reversal drug. Researchers will measure how quic…

This observational study looks at whether sarcopenia (muscle loss) and frailty affect how the muscle relaxant rocuronium works in older patients having surgery. Researchers will monitor 100 adults aged 65 and older to see how fast the drug takes effect and how long it lasts. The …

This study tests a new device that measures how relaxed a patient's muscles are during surgery. The goal is to see if it works as well as the standard monitor, but is easier to set up and use. About 100 adults having planned surgery will take part. The study does not test a treat…

This study compares two muscle relaxant drugs (rocuronium and cisatracurium) used during general anesthesia in people with chronic kidney disease. Researchers want to see which drug leads to fewer lung problems after surgery. About 490 adults with kidney disease will take part.

This study looks at two different ways to measure how well muscles recover from deep paralysis during surgery. About 199 adults aged 18-65 with a healthy weight will take part. The goal is to see which measurement method better ensures it is safe to remove the breathing tube afte…

This study compares using the median nerve versus the ulnar nerve to monitor how relaxed a patient's muscles are during surgery. Researchers will measure the muscle response to nerve stimulation in 32 adults having elective surgery. The goal is to see if the median nerve works as…

This study is testing a new method for giving muscle relaxants to patients with severe breathing problems who are on a breathing machine. The goal is to see if this approach is safe and possible, and if it helps patients breathe on their own more easily. About 23 adults in the ho…