Heart surgery fluid showdown: which one spares kidneys?

NCT ID NCT07410988

Recruiting now Disease control Sponsor: Seoul National University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 31, 2026 · Updated 4 times

Summary

This large trial tests two types of intravenous fluids given during heart surgery: hydroxyethyl starch (HES) and balanced crystalloids. The goal is to see which fluid leads to fewer serious kidney problems, such as kidney failure or death. About 1,292 adults having heart surgery will take part, and their kidney health will be tracked afterward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hydroxyethyl starch (HES) and balanced crystalloid solutions
What this could lead to: If it works, this could show that one fluid is safer for the kidneys during heart surgery, helping doctors choose better options.
What could go wrong: This is a phase 4 trial, but results may not apply to all patients or surgeries. HES has known kidney risks in some settings, and the benefit may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart valve disorder thoracic aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY

Contacts and locations

Locations

Chungnam National University Hospital
RECRUITING

Daejeon, 35015, South Korea
Korea University Guro Hospital
RECRUITING

Seoul, 03080, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Severance Hospital
RECRUITING

Seoul, 03080, South Korea

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