Heart surgery fluid showdown: which one spares kidneys?
NCT ID NCT07410988
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This large trial tests two types of intravenous fluids given during heart surgery: hydroxyethyl starch (HES) and balanced crystalloids. The goal is to see which fluid leads to fewer serious kidney problems, such as kidney failure or death. About 1,292 adults having heart surgery will take part, and their kidney health will be tracked afterward.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydroxyethyl starch (HES) and balanced crystalloid solutions
What this could lead to
If it works, this could show that one fluid is safer for the kidneys during heart surgery, helping doctors choose better options.
What could go wrong
This is a phase 4 trial, but results may not apply to all patients or surgeries. HES has known kidney risks in some settings, and the benefit may be small.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chungnam National University Hospital
RECRUITINGDaejeon, 35015, South Korea
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Korea University Guro Hospital
RECRUITINGSeoul, 03080, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, 03080, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Severance Hospital
RECRUITINGSeoul, 03080, South Korea