Gout drug tapering trial: could patients finally take less medicine?

NCT ID NCT06622603

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether people with well-controlled gout (for at least 5 years) can safely reduce or stop their daily febuxostat. Fifty-nine adults will be split into three groups: one that lowers the dose, one that stops for 6 months then restarts a lower dose, and one that stays on their usual treatment. Researchers will track uric acid levels and any symptom return over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

febuxostat

What this could lead to

If successful, this could show that some gout patients can safely lower their medication dose without flare-ups, simplifying long-term management.

What could go wrong

This is a small, early-phase trial with only 59 participants. Results may not apply to all gout patients, and reducing medication could still cause symptom return or high uric acid levels.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gout

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam-si, Gyeonggi-do, 463-707, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••