New strategy aims to shield myeloma patients from dangerous virus during treatment
NCT ID NCT06920251
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether the antiviral drug letermovir can prevent a common and serious viral infection called CMV in people with relapsed/refractory multiple myeloma who are receiving the immunotherapy elranatamab. The trial will enroll 40 adults who are CMV-positive. Researchers will monitor how many patients develop a significant CMV infection during treatment. If letermovir works, it could become a standard preventive measure for these patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Letermovir (an antiviral drug) and elranatamab (a cancer immunotherapy)
- What this could lead to
- If successful, this could provide a way to prevent a serious viral infection (CMV) in multiple myeloma patients undergoing treatment, reducing hospitalizations and complications.
- What could go wrong
- This is a small, early-phase study with only 40 participants, so results may not apply to all patients. The drug may not effectively prevent CMV or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Seoul National University Hospital
RECRUITINGSeoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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