Ohio State University
Clinical trials sponsored by Ohio State University, explained in plain language.
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Sleep pill studied to calm stress and curb drinking
Disease control CompletedThis study tested if suvorexant, a medication used for insomnia, could help people with moderate to severe alcohol use disorder. Researchers wanted to see if the drug could reduce the brain's overreaction to stress and lower heavy drinking days. 81 participants took either the dr…
Phase: EARLY_PHASE1 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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ERs test special team approach to stop older patients from declining after visits
Disease control CompletedThis study tested a two-step program in an emergency department to better care for patients aged 65 and older. First, nurses quickly screened patients for risks like falls, confusion, and frailty. Those with concerning results received a more thorough assessment from a specialize…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New monitor could free up ICU nurses from constant finger pricks
Disease control CompletedThis study tested whether using a continuous glucose monitor (CGM) in the intensive care unit (ICU) is practical and helpful. It compared 100 ICU patients using the CGM to 100 past patients who used traditional fingerstick checks. The goal was to see if the CGM improved blood sug…
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Mindfulness & diet program aims to ease double burden for black caregivers
Disease control CompletedThis small, completed pilot study tested a telehealth program designed to help Black women who are caregivers for family members with dementia. The program combined mindfulness exercises and a heart-healthy diet plan (DASH) to see if it could help them manage their chronic stress…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Can grocery delivery and counseling help control chronic disease?
Disease control CompletedThis study tested a 24-week support program for Medicaid patients with conditions like high blood pressure, diabetes, and kidney disease. The program provided healthy food access, nutrition counseling, and grocery delivery to see if it helped people stick to healthier habits. Res…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Could a buddy system boost weight loss surgery success?
Disease control CompletedThis study tested if having a support person, like a partner or friend, attend medical appointments with patients getting weight loss surgery could help. Researchers wanted to see if this support led to better weight loss, healthier eating, and more exercise after surgery compare…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Can a cup of green tea fix your gut and fight inflammation?
Disease control CompletedThis study tested whether taking a green tea extract supplement for one month could improve gut health and reduce harmful inflammation in people with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. Forty-six participants, including some …
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Could a milk ingredient fix your gut and lower blood sugar?
Disease control CompletedThis study tested whether adding a natural component from milk fat (MFGM) to the diet could help adults with metabolic syndrome. Participants drank either the special milk or a regular milk for two weeks while eating a controlled diet. Researchers measured blood sugar, gut health…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Can a phone app curb campus binge drinking?
Disease control CompletedThis study tested a new program called IMPROVE, designed to help college students who drink heavily and feel stressed. The program teaches skills to better handle anxiety and uncertainty, aiming to reduce the urge to use alcohol as a coping method. Researchers compared the progra…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Feb 20, 2026 14:44 UTC
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Eye dilation study aims for clearer vision for down syndrome community
Diagnosis CompletedThis study tested whether dilating the eyes (using drops to widen the pupil) gives a better measurement for glasses prescriptions in people with Down syndrome. People with Down syndrome often have unique eye shapes that make standard vision tests less accurate. Researchers compar…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Diagnosis
Last updated Mar 27, 2026 12:40 UTC
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Can a home stop addiction before it starts? landmark trial tests housing as prevention for homeless youth
Prevention CompletedThis study tested whether providing stable housing along with counseling and support services could prevent opioid addiction in homeless young adults. Researchers worked with 240 homeless youth aged 18-24 who were not yet addicted to opioids. They compared two groups: one receive…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 30, 2026 14:35 UTC
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Virtual lifeline for teens in crisis: can a One-Hour plan save lives?
Prevention CompletedThis study tested whether a one-hour virtual crisis planning session could help prevent suicide in teens. It involved 57 adolescents who were actively thinking about suicide. Researchers compared the virtual session to an in-person version and standard care to see which was more …
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 24, 2026 12:02 UTC
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Can mindfulness ease the heavy burden on our first responders?
Symptom relief CompletedThis study tested whether a mindfulness program could help first responders manage job stress and physical discomfort. Twenty-nine active first responders participated in an 8-week virtual mindfulness course and used a companion app for six months. Researchers measured changes in…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Which contact lens feels better? study tests two brands
Symptom relief CompletedThis study compared how comfortable two different brands of reusable contact lenses feel for people with nearsightedness. 71 participants who normally wore Acuvue Oasys lenses tried Precision7 lenses for two weeks. Researchers measured comfort levels through vision tests and surv…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Pocket-Warmed pain relief: a faster start for laboring moms?
Symptom relief CompletedThis study tested a simple idea: does warming epidural pain medication in a doctor's pocket before giving it help the medicine work faster for women in labor? Researchers enrolled 139 women to compare the speed of pain relief between warmed and room-temperature medication. The go…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Finding the right dose: study tests pain relief options for new moms after C-Section
Symptom relief CompletedThis study aimed to find the best dose of the pain medication ketorolac for women recovering from cesarean delivery. Researchers compared whether a 30mg or 60mg dose given right after surgery better reduced the need for opioid painkillers in the first 24 hours. The trial involved…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Which numbing shot hurts less before your epidural?
Symptom relief CompletedThis study aimed to find out which method of giving a numbing shot causes less pain right before placing the epidural needle during labor. Researchers compared injecting lidocaine just under the skin versus into a deeper skin layer in 51 women in labor. They measured pain using p…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Could a new daily lens feel better than your monthly ones?
Symptom relief CompletedThis study tested how comfortable a new type of daily disposable contact lens felt for people who usually wear monthly lenses. Thirty-four participants tried the new lenses, which have a special water surface treatment. Researchers asked them to rate their comfort to see if the d…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Could a common drug clear long COVID brain fog?
Symptom relief CompletedThis study tested whether amantadine, an existing medication, could help improve thinking problems like memory loss and poor concentration (often called 'brain fog') in people with Long COVID. For four months, 64 participants were randomly assigned to receive either amantadine or…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Papaya put to the test: is it a superfood for nutrient absorption?
Knowledge-focused CompletedThis study aimed to find out if papaya is a better source of carotenoids (healthy plant nutrients) than more common foods like carrots and tomatoes. Researchers measured nutrient levels in the blood of 16 healthy volunteers after they ate meals containing these foods. The goal wa…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 02, 2026 05:42 UTC
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Scientists scan brains to unlock how mindfulness helps trauma
Knowledge-focused CompletedThis study aimed to understand how mindfulness-based therapy affects brain activity in people with post-traumatic stress disorder (PTSD). Researchers compared two types of group therapy delivered over 8 weeks via video calls. They used brain scans and surveys to measure changes b…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Can we treat the 'Brain Fog' of long COVID?
Knowledge-focused CompletedThis study looked back at 171 patients with Long COVID who had thinking and memory problems, often called 'brain fog.' Researchers tracked what treatments these patients received at a special clinic, like therapy or medications, and checked if their quality of life and thinking s…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Dental study pits two Bone-Building methods Head-to-Head
Knowledge-focused CompletedThis study compared two established surgical techniques used to build up jawbone before placing a dental implant. Researchers observed 28 healthy adults to see if one method led to better healing, higher bone density, or a more comfortable patient experience. The study did not ch…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Could your Pre-Surgery diet affect your brain afterward?
Knowledge-focused CompletedThis study looked at whether eating a high-fat diet before major surgery is linked to higher body inflammation and an increased risk of thinking problems or confusion after the operation. Researchers enrolled 62 older adults having surgeries like joint replacements or abdominal p…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Eggs unlock the power of spinach: study finds key to boosting vitamin e
Knowledge-focused CompletedThis study aimed to see if eating eggs with spinach helps your body absorb more Vitamin E, a nutrient many people don't get enough of. Researchers gave healthy volunteers spinach with different amounts of eggs or other fats and then measured Vitamin E levels in their blood over s…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Can a special reading plan unlock literacy for deaf kids?
Knowledge-focused CompletedThis study tested whether a home-based reading program could help young children with hearing loss learn early reading skills. Fifteen families participated, with caregivers trained to read to their child four times a week using specific techniques. The goal was to see if this ap…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Can a quick brain game predict Post-Surgery confusion?
Knowledge-focused CompletedThis study tested whether a short, 6-game brain exercise on a tablet is practical to use in busy pre-surgery areas. Researchers wanted to see if a patient's score on these games could help predict their risk of developing delirium (a state of sudden confusion) after a major opera…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Scientists probe why glaucoma drugs fail some patients
Knowledge-focused CompletedThis study aimed to find out why people with glaucoma or high eye pressure respond differently to standard eye drop medications. Researchers measured how fluid moves in and out of the eye in 59 participants to see if they could predict who would have a good or poor response to tw…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Scientists scan brains to see how autism therapy works
Knowledge-focused CompletedThis small pilot study aimed to understand what happens in the brain during occupational therapy for children with autism. Researchers measured brain activity and behavior in children before and after 6-8 weeks of standard therapy. The goal was to see if a child's level of engage…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Scientists map nerve damage in muscle disease to find better treatments
Knowledge-focused CompletedThis study aimed to understand how spinal muscular atrophy (SMA) progresses in adults by measuring electrical signals from their nerves and muscles. Researchers followed 67 adults with SMA, some receiving a new drug and some not, to see how these measurements changed over time. T…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC
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Scientists ask: could online mindfulness help prevent memory loss?
Knowledge-focused CompletedThis study aimed to design online mindfulness and healthy living programs for adults over 50 who are worried about their memory but still test normally. Researchers held focus groups with 23 participants to get their feedback on the program content and website design. The goal wa…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:51 UTC
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Researchers test video game-like app to teach kids diabetes care
Knowledge-focused CompletedThis study tested whether a new mobile app could help youth with type 1 diabetes learn to better manage their condition. Twenty participants aged 10-18 used the app at home for 12 weeks, completing interactive simulations about their diabetes care. Researchers measured how often …
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:53 UTC
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Researchers test if special contact lenses can help young adults focus their eyes
Knowledge-focused CompletedThis study aimed to understand how different designs of multifocal contact lenses affect the eye's ability to focus, particularly for people with focusing problems. Researchers compared two lens types—one designed for near vision in the center and another for distance vision in t…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 05, 2026 13:59 UTC