Ohio State University
Clinical trials sponsored by Ohio State University, explained in plain language.
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Can stress relief protect black Women's hearts? new study says yes
Disease control CompletedThis study tests a program called B-SWELL that helps midlife Black women (ages 45-64) lower their heart disease risk by reducing stress and adopting healthier habits. About 43 women from the Cincinnati area will be randomly placed into either the B-SWELL program or a general well…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jul 01, 2026 23:00 UTC
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Sleeve that reads muscle signals may restore hand grasp in paralysis
Disease control CompletedThis pilot study tested a sleeve worn on the forearm that uses muscle signals to stimulate hand muscles, helping people with tetraplegia from spinal cord injury grasp and manipulate objects. Twelve adults with chronic cervical SCI completed a 12-week training program using the de…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Teens helping teens: peer mentors aim to boost fitness in appalachian high schools
Disease control CompletedThis study tested whether training older high school students as peer mentors could help younger teens become more physically active. Over 500 students from Appalachian high schools took part, comparing a peer-mentored program to a teacher-led one. The goal was to see if the ment…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New program aims to prevent nurse suicide by pairing online screening with resilience training
Disease control CompletedThis study tested whether an online screening tool (mISP) alone or combined with a mental health skills program (MINDBODYSTRONG) can reduce suicide risk and depression in nurses. About 849 nurses who were at moderate to high risk for suicide took part. The program teaches coping …
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Smart patch could help nurses manage blood sugar in ICU
Disease control CompletedThis study tested whether a continuous glucose monitor (CGM) could help nurses manage blood sugar in ICU patients receiving IV insulin. Researchers enrolled 201 adults with high blood sugar or on insulin at Ohio State University. The goal was to see if using the CGM alongside sta…
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Green tea extract shows promise for gut health in metabolic syndrome
Disease control CompletedThis study tested whether taking green tea extract for one month could improve gut health and reduce inflammation in people with metabolic syndrome and in healthy adults. Participants took either the extract or a placebo for a month, then switched. The study measured markers of i…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Milk membrane may tame metabolic syndrome inflammation
Disease control CompletedThis study looked at whether a natural part of milk fat called milk fat globule membrane (MFGM) can lower harmful gut bacteria products in the blood and improve health markers in adults with metabolic syndrome. Thirty people with metabolic syndrome followed a controlled diet with…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Sleep drug suvorexant shows promise for curbing heavy drinking in early trial
Disease control CompletedThis early-phase study tested whether suvorexant (Belsomra), a sleep medication, can reduce stress sensitivity and heavy drinking in 81 adults with moderate to severe alcohol use disorder. Participants took either suvorexant or a placebo for 4 weeks, and researchers measured thei…
Phase: EARLY_PHASE1 • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Bring a buddy to boost bariatric success?
Disease control CompletedThis study looked at whether having a partner or support figure attend clinic visits before and after bariatric surgery helps patients lose more weight and make healthier choices. 63 adults seeking weight-loss surgery were randomly assigned to bring a support person or not. Resea…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Mindfulness may lower blood pressure in black women caring for loved ones with dementia
Disease control CompletedThis pilot study tested a telehealth program combining mindfulness, relaxation, and dietary advice (MIM-DASH) in 28 African American women over 40 who care for a family member with Alzheimer's and have high blood pressure. The goal was to see if the program could reduce stress an…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 26, 2026 18:00 UTC
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Kids' garden program could sow seeds for healthier futures
Prevention CompletedThis study tests a summer garden program called 'Summer Harvest Adventure' for children aged 8 to 11 from low-resource communities. The program teaches nutrition and healthy habits through gardening and cooking activities. Researchers will measure changes in fruit and vegetable i…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Jul 01, 2026 23:00 UTC
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Housing first: a bold experiment to stop opioid addiction before it starts
Prevention CompletedThis study tested whether giving homeless young people (ages 18-24) a place to live plus support services could help them avoid developing opioid use disorder. 240 participants who were homeless but did not yet have opioid addiction were randomly assigned to receive either housin…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Jun 26, 2026 17:04 UTC
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Can a daily pill give you better skin?
Symptom relief CompletedThis study tested whether an oral herbal supplement called PrimaVie can improve skin blood flow, hydration, elasticity, and barrier function. 45 healthy women aged 30-65 took either a low dose, high dose, or placebo pill twice daily for 14 weeks. Researchers measured skin changes…
Phase: PHASE1 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Fish oil supplements show promise for stubborn leg ulcers
Symptom relief CompletedThis study tested whether taking fish oil supplements (EPA and DHA) could help heal chronic venous leg ulcers in adults aged 55 and older. The idea was that fish oil might reduce inflammation at the wound site, allowing the ulcer to heal. Researchers measured changes in blood mar…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Dance students find relief: Mind-Body course cuts stress and burnout
Symptom relief CompletedThis study tested an 8-week mind-body program called Mindfulness in Motion (MIM) in 37 university dance students. The course taught stress reduction, mindfulness, and gentle yoga to help students handle physical and emotional pressures. Researchers measured changes in stress, bur…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New contact lens trial offers hope for astigmatism sufferers
Symptom relief CompletedThis study tested how well people with astigmatism who had never worn contact lenses liked a new type of soft lens that is replaced every week. Forty adults wore the lenses for about three weeks and reported on their vision and comfort. The goal was to see if these lenses could b…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Physical therapy after hernia surgery shows promise in small trial
Symptom relief CompletedThis study looked at whether a special physical therapy program for the core muscles could help people recover after surgery for a ventral hernia. 138 adults who were scheduled for hernia repair took part. The main goal was to see if the therapy improved their mobility and physic…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can parents boost autism therapy at home? small study investigates
Symptom relief CompletedThis study looked at whether teaching parents to use Reciprocal Imitation Training (RIT) at home helps young children with autism improve their imitation and social skills more than therapist-only sessions. Eighteen children aged 2 to 5 years participated. The goal was to see if …
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Fasting for clearer skin? study tests Time-Restricted eating for psoriasis
Symptom relief CompletedThis study looked at whether intermittent fasting (eating only during certain hours) can reduce disease severity and improve quality of life for people with psoriasis and psoriatic arthritis. Sixty overweight adults were randomly assigned to either follow an intermittent fasting …
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Can a One-Hour chat help teens at risk for suicide?
Symptom relief CompletedThis study tested whether a single, one-hour crisis response planning session—done either virtually or in-person—could help teens (ages 14-18) who are thinking about suicide. Fifty-seven participants were randomly assigned to virtual crisis planning, in-person crisis planning, or…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Pocket trick may speed epidural relief for moms in labor
Symptom relief CompletedThis study tested whether warming epidural medication by keeping it in a pocket before injection helps it work faster for labor pain. Researchers compared pocket-warmed medication to standard care in 139 women. The goal was to see how quickly pain dropped to a low level and how s…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Higher dose of painkiller may cut morphine use after C-Section
Symptom relief CompletedThis study tested whether a higher dose of ketorolac (60 mg vs. 30 mg) given right after C-section reduces the need for morphine in the first 24 hours. 92 women who had a C-section under regional anesthesia took part. The goal was to find a better way to manage pain while lowerin…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Needle poke showdown: which lidocaine method hurts less for moms in labor?
Symptom relief CompletedThis study looked at 51 women in labor who wanted an epidural for pain relief. Researchers compared two standard ways of numbing the skin (injecting lidocaine under the skin or into the skin) before inserting the epidural needle. The goal was to see which method caused less pain …
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New Anxiety-Focused program aims to curb binge drinking on campus
Symptom relief CompletedThis study tested a behavioral program called IMPROVE to help college students who drink heavily and feel anxious. The program teaches skills to handle anxiety and uncertainty without turning to alcohol. Forty students took part, and researchers checked if the program was easy to…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can a common drug clear long COVID brain fog?
Symptom relief CompletedThis study tested whether amantadine, a medication used for other conditions, can improve memory and thinking problems in people with Long COVID. 64 adults with lasting cognitive issues after a COVID infection took part. Researchers also looked for lab markers that might predict …
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New daily contact lenses put to the comfort test
Symptom relief CompletedThis study looked at how comfortable daily disposable contact lenses with a water surface treatment feel compared to monthly lenses. Thirty-four people who already wear monthly lenses tried the daily ones and rated their comfort on a scale. The goal was to see if the new lenses i…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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New contact lens study aims for fresher, more comfortable eyes
Symptom relief CompletedThis study tested whether switching from Acuvue Oasys contact lenses to PRECISION7 lenses improves comfort and reduces dry eye symptoms. Seventy-one adults who were happy with their current lenses wore PRECISION7 lenses for two weeks. They completed surveys about their experience…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Mindfulness program shows promise for stressed first responders
Knowledge-focused CompletedThis study tested an 8-week mindfulness program for 29 first responders (like police and firefighters) to see if it could lower stress, boost resilience, and reduce body pain. Participants used a smartphone app and attended virtual sessions. The goal was to learn whether this app…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Special contact lenses may slow nearsightedness in kids
Knowledge-focused CompletedThis study followed 248 children with nearsightedness who wore soft bifocal contact lenses for two years and then switched to regular lenses for a third year. Researchers measured eye growth, light exposure, and pupil responses to understand why some children's nearsightedness ge…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Study tests which marijuana tax curbs consumption best
Knowledge-focused CompletedThis completed study from Ohio State University looked at how different tax structures—based on weight, price, or potency—might change marijuana buying habits. Researchers surveyed nearly 4,700 adults and teens, asking them to make hypothetical purchases under various tax scenari…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Better glasses for down syndrome? study tests eye dilation trick
Knowledge-focused CompletedThis study looked at whether using eye drops to dilate (widen) the pupils before measuring vision leads to better eyeglass prescriptions for people with Down syndrome. 42 participants had their vision tested with and without dilation. The goal was to see which method gives sharpe…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Brain scans reveal how a brief crisis plan may lower suicide risk
Knowledge-focused CompletedThis study tested whether a one-hour crisis response planning session can reduce suicide risk more than standard care. 191 adults with current suicidal thoughts were randomly assigned to either the crisis plan or usual risk management. Researchers used brain scans and surveys to …
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New strategy aims to stop missed dizziness diagnoses in ERs
Knowledge-focused CompletedThis study looked at how to improve care for dizzy patients in the emergency department. Over 90,000 adults participated. The goal was to help doctors use proven tests and treatments for common causes of dizziness like BPPV. The study tested new training and tools to make sure pa…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Wearable tech reveals links between sitting and quality of life
Knowledge-focused CompletedThis study looked at how physical activity relates to quality of life and mental health in 38 adults with severe obesity (BMI over 40). Participants wore activity monitors for 6 weeks to track sitting, standing, and movement. The goal was to see if simply monitoring activity coul…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can a web program help parents of preemie toddlers?
Knowledge-focused CompletedThis study tested a web-based parent training program called ezParent, with or without extra telephone coaching, for parents of toddlers born very premature (before 32 weeks). Over 450 parents took part, and researchers measured changes in parenting skills, stress, and child beha…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Virtual skin checks may save patients from unnecessary hospital stays
Knowledge-focused CompletedThis study looked at whether having a dermatologist review a patient's skin condition remotely (teledermatology) could help emergency room doctors correctly identify true cellulitis (a bacterial skin infection) versus pseudocellulitis (a condition that looks like cellulitis but i…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New toolkit aims to bridge child welfare and addiction services
Knowledge-focused CompletedThis study tested a digital toolkit designed to help leaders in child welfare and substance use treatment agencies choose partners and build effective collaborations. Nine implementation support professionals in Ohio used the guide and rated how acceptable, appropriate, and feasi…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Brain scans reveal how mindfulness rewires PTSD Patients' minds
Knowledge-focused CompletedThis study looked at how mindfulness-based cognitive therapy (MBCT) changes brain activity in 61 adults with PTSD. Participants received either MBCT or a mind-body comparison therapy, and researchers used fMRI scans to measure brain connectivity before and after treatment. The go…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Scientists probe eye fluid secrets to personalize glaucoma treatment
Knowledge-focused CompletedThis study looked at how the eye produces and drains fluid to understand why glaucoma medications lower eye pressure more in some people than others. Researchers measured eye fluid production, drainage, and pressure in 59 adults with glaucoma or high eye pressure before and after…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Could your Pre-Surgery diet affect your brain?
Knowledge-focused CompletedThis study looked at whether eating fatty foods before major surgery is linked to inflammation and memory or thinking problems in older adults. Researchers tracked the diets and health of 62 people aged 60 and older having major abdominal, pelvic, or joint surgery. The goal was t…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Long COVID brain fog study tracks Real-World treatment outcomes
Knowledge-focused CompletedThis study followed 171 people with Long COVID who had brain fog and other thinking problems. Researchers looked at what treatments patients received and how their quality of life changed over 6 months. The goal was to see if certain treatments helped improve daily functioning. B…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New tests could reveal how SMA progresses in adults
Knowledge-focused CompletedThis study looked at 67 adults with spinal muscular atrophy (SMA) types 2 and 3 to see if special electrical tests (MUNE and CMAP) can track nerve loss over time. The goal was to find better ways to measure how the disease changes, not to test a treatment. Participants had geneti…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Brain games before surgery: a new way to spot delirium risk?
Knowledge-focused CompletedThis study tested whether older adults (60+) scheduled for major surgery could complete a set of six brain exercise games on a tablet before their operation. The goal was to see if this was practical in a busy clinic or hospital setting and whether the first-time game scores coul…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Dental implant study pokes into best way to beef up jawbone
Knowledge-focused CompletedThis study looked at two common techniques dentists use to add bone to the jaw before placing a dental implant. Researchers compared how well the gum healed, how dense the new bone became, and how patients felt during and after surgery. The study did not change which technique pa…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New ED protocol aims to better care for older patients at risk of falls and delirium
Knowledge-focused CompletedThis study tested a two-step process to improve care for older adults in the emergency department. First, quick screening tests for fall risk, delirium, and frailty were used. Patients with concerning results were then placed in an observation unit for a full team assessment by g…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Contact lens study reveals new insights on eye focusing problems
Knowledge-focused CompletedThis study looked at how different types of multifocal contact lenses change the way young adults focus their eyes. Twenty people aged 18 to 30 with no other eye problems took part. Researchers measured eye focusing and teaming while participants wore two kinds of lenses. The goa…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Can online mindfulness help aging brains? new study lays groundwork
Knowledge-focused CompletedThis study worked with 23 adults aged 50 and older who have memory concerns to design online mindfulness and lifestyle education programs. Participants joined focus groups to share their views on healthy living and web-based interventions. Their feedback will help shape future cl…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Reading program shows promise for kids with hearing loss
Knowledge-focused CompletedThis study tested a home-based reading program called Sit Together and Read (STAR) in 15 preschoolers with hearing loss. Caregivers read with their child for 15 weeks using special techniques to teach print concepts and letter knowledge. The goal was to see if the program is feas…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Food as medicine: study tests grocery vouchers for High-Risk patients
Knowledge-focused CompletedThis study tested whether giving Medicaid patients with stage 2 cardiovascular-kidney-metabolic syndrome (CKMS) access to healthy food through Instacart vouchers and food banks, plus nutrition counseling, is practical and engaging. Over 24 weeks, researchers measured how many peo…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Eggs unlock spinach's vitamin e power, study finds
Knowledge-focused CompletedThis study looked at whether eating eggs with spinach helps the body absorb more vitamin E, a nutrient many people don't get enough of. Eight healthy adults ate specially labeled spinach alone or with eggs. Researchers measured how much vitamin E got into their blood. The goal wa…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Tiny study peers inside the brain during autism therapy
Knowledge-focused CompletedThis pilot study looked at how routine occupational therapy changes brain activity and behavior in children with autism. Two children received weekly one-hour therapy sessions for 6-8 weeks. Researchers used EEG to measure brain responses and parent questionnaires to track social…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Papaya, carrot, tomato showdown: which fruit delivers more nutrients?
Knowledge-focused CompletedThis study looked at whether papaya is a better source of carotenoids (nutrients that give fruits and vegetables their color) than carrots or tomatoes. Sixteen healthy adults ate meals containing one of these foods, and researchers measured how much of the nutrients got into thei…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Can a smartphone app teach teens to manage diabetes?
Knowledge-focused CompletedThis study tested a mobile app designed to help young people with type 1 diabetes learn how to manage their condition. Twenty teens aged 10-18 used the app at home for 12 weeks. Researchers measured how often they used the app and checked their blood sugar control.
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC