Ohio State University
Clinical trials sponsored by Ohio State University, explained in plain language.
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New gum patch tested to heal receding gums without a second surgery
Disease control OngoingThis study is testing a new version of a processed tissue material used to cover exposed tooth roots (gum recession). It compares the new material to the standard version to see if it improves healing, coverage, and patient comfort. The goal is to offer an alternative to taking t…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Titanium vs. plastic: the battle for a better backbone
Disease control OngoingThis study is testing whether a new type of textured titanium cage works better than the standard plastic cage for spinal fusion surgery. It involves 100 adults with severe back problems who haven't improved with other treatments. Researchers will follow patients for two years to…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New program aims to stop psychosis before it starts
Disease control ENROLLING_BY_INVITATIONThis study is evaluating a specialized care program for young people aged 12-25 who show early warning signs of psychosis, a serious mental health condition. Researchers will follow 100 participants for up to two years to see if the program helps reduce their risk symptoms and im…
Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Double duty: new program aims to ease stress and lower blood pressure for black women caring for loved ones with dementia
Disease control OngoingThis study is testing two different wellness programs delivered through video calls to help Black women who are caregivers for family members with dementia. The programs combine mindfulness exercises with a heart-healthy eating plan tailored for Black Americans. Researchers want …
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Eye drops vs. special contacts: the battle to halt worsening vision
Disease control OngoingThis study is investigating whether two common treatments—low-dose atropine eye drops or special multifocal contact lenses—can slow the progression of nearsightedness in young adults. Researchers are measuring how these treatments change the shape of the eye over one year. They a…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Can a common cooking oil shrink dangerous liver fat?
Disease control OngoingThis study is testing whether eating foods containing soybean oil every day for 16 weeks can reduce harmful fat buildup in the liver. It involves 74 adults diagnosed with nonalcoholic fatty liver disease. Researchers will use MRI scans to see if the oil helps lower liver fat and …
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Family teamwork tested to fight diabetes
Disease control OngoingThis study tests whether a family-focused coaching program helps African American adults better manage their type 2 diabetes. Participants and a family member attend virtual group sessions about diabetes care and support over 12 weeks. Researchers measure changes in blood sugar c…
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 09, 2026 14:26 UTC
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One-Hour brain scan study tests new suicide prevention talk
Prevention OngoingThis study is testing whether a single 1-hour crisis planning session can help prevent suicide. Researchers are comparing this brief talk to standard care in adults who are currently thinking about suicide. They will use brain scans and surveys to see how the session affects brai…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 31, 2026 12:11 UTC
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Teen mentors step up to fight childhood obesity in struggling rural communities
Prevention OngoingThis study tests whether a program using older teen mentors and family support can help overweight 7th graders in rural Appalachia become more physically active and improve their health. The program provides culturally appropriate guidance to build exercise habits without needing…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Can a fitbit keep the doctor away? seniors test wearable tech for health
Prevention OngoingThis study is testing whether giving Fitbit smartwatches to adults aged 65 and older makes it easier and more appealing for them to follow a doctor-referred exercise program. The main goal is to see if using the technology is practical and acceptable for this age group, with the …
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Can yoga and mindfulness help dancers beat burnout and injury?
Symptom relief OngoingThis study is testing whether an 8-week course combining mindfulness, gentle yoga, and group discussion can help university dance students. The course aims to reduce their perceived stress, burnout, and physical discomfort while building resilience. Researchers will measure these…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 01, 2026 23:11 UTC
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Magic mushroom therapy tested for Veterans' trauma
Symptom relief OngoingThis study is testing whether psilocybin, the active compound in 'magic mushrooms,' combined with therapy, is safe and helpful for military veterans with PTSD. Fifteen veterans will receive two guided psilocybin sessions along with therapy before and after. Researchers will track…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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New study probes if scope procedure can ease debilitating pancreas pain
Symptom relief OngoingThis study aims to see if a procedure called pancreatic endotherapy helps people with painful chronic pancreatitis feel better. Researchers will follow 32 patients for a year to measure changes in their pain levels, daily life quality, and pancreas function after the procedure. T…
Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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New training could help lung transplant patients breathe easier
Symptom relief OngoingThis study is testing whether a special breathing exercise program helps people recover after a lung transplant. Researchers will compare patients who do the breathing training along with standard physical therapy to those who only get standard therapy. The goal is to see if the …
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Can online training and phone calls help parents of premature toddlers?
Symptom relief OngoingThis study is testing whether a web-based parenting program called ezParent, with or without weekly phone coaching, can help parents of toddlers who were born very premature. Researchers want to see if these tools improve parents' confidence and skills, reduce parenting stress, a…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 09, 2026 14:26 UTC
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Wearable tech aims to predict soldier recovery from back pain
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand back and neck pain better by comparing people with pain to those without. Participants will wear a motion monitor and answer questionnaires to see if movement data can predict recovery and return to work. The study will follow 400 military personnel …
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 01, 2026 23:11 UTC
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Bread battle: can whole wheat tame your gut and blood sugar?
Knowledge-focused OngoingThis study aims to understand why whole wheat bread helps lower blood sugar for some people with prediabetes but not others. Researchers are comparing the effects of eating whole wheat bread versus white bread for two weeks at a time in 65 adults with prediabetes. They will colle…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 01, 2026 23:11 UTC
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Can a video game Doctor's visit work? study tests virtual arm exams for kids
Knowledge-focused OngoingThis study is checking if a play-based test for arm and hand movements gives the same results when done over a video call (telehealth) as it does in person for children with hemiplegic cerebral palsy. 35 children, aged 2-10, will attend two visits—one in-person and one via telehe…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists track eyes to see what makes a good batter
Knowledge-focused OngoingThis research study aims to understand how experienced baseball players watch a pitcher compared to people with no experience. Researchers will track the eye movements of 21 participants as they watch videos of pitches. The goal is to learn if skilled players have a more stable, …
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Scientists test new ways to measure your Body's energy in a drop of blood
Knowledge-focused OngoingThis study aims to improve the methods for measuring fats and energy production in blood samples. Healthy adult volunteers provide blood samples from a vein and from a simple finger prick, including one kit sent by mail. The goal is to make these lab tests more reliable and easie…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Could your genes predict your stroke recovery?
Knowledge-focused OngoingThis study aims to understand why some people with aphasia (language problems after a stroke) respond better to therapy than others. Researchers will test 120 people to see if specific genes and memory skills can predict how well someone improves with word-retrieval therapy. The …
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Can a needle trick your brain? study probes knee pain mystery
Knowledge-focused OngoingThis study aims to understand how chronic pain in both knees affects the brain's ability to tell left from right and how a treatment called dry needling might influence muscle function and movement. Researchers will compare 60 adults, including people with knee pain (with high or…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Can cash bonuses make addiction counseling better?
Knowledge-focused OngoingThis study tests whether paying bonuses to staff at HIV service organizations improves how they deliver a brief counseling method for substance use. It involves 428 staff and clients across the U.S. The main goal is to see if this 'pay-for-performance' strategy leads to more cons…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Do popular drugs work the same for men and women? massive study investigates
Knowledge-focused OngoingThis study uses existing health records from over 23 million people to see if two types of medications (GLP-1 agonists like Ozempic and SGLT2 inhibitors) work differently for men and women. It aims to find out if one sex gets more benefit in preventing heart attacks, strokes, kid…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Scientists test strawberry gummies to fight gum disease
Knowledge-focused OngoingThis early-stage study is testing two types of strawberry gummies to understand how the mouth absorbs their compounds and whether they might benefit oral health. Researchers will enroll 36 adults, both smokers and non-smokers, who will eat the gummies daily for a week while follo…
Phase: PHASE1 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Scientists scan teen brains to uncover hidden links between early exposures and future mental health
Knowledge-focused OngoingThis study aims to understand how exposure to chemicals and stress during pregnancy might affect brain development and increase risk for mental health issues during the teenage years. Researchers will use brain scans and behavioral assessments on 250 adolescents who have existing…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Virtual reality vs. stigma: can seeing through a Patient's eyes change pharmacy care?
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing a new computer-based training simulation designed to help pharmacists and pharmacy students better understand the experiences of people with sickle cell disease who need pain medication. Researchers want to see if experiencing a virtual scenario from the pat…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC
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Orange tomatoes: are they a better source of healthy nutrients?
Knowledge-focused OngoingThis study aims to find out if the body absorbs healthy nutrients more easily from a unique orange tomato variety called Tangerine, compared to common red tomatoes. Researchers will measure nutrient levels in the blood and urine of 12 healthy adults after they drink either Tanger…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:52 UTC
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Study withdrawn: researchers planned to track blood sugar in pregnancy
Knowledge-focused TerminatedThis study aimed to gather detailed blood sugar data from pregnant people with gestational diabetes who needed medication. It planned to compare glucose patterns between those taking metformin pills and those using insulin injections. The goal was to see if one medication led to …
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 03, 2026 14:07 UTC