Sip your way sharper? ketone drink tested against sleep loss

NCT ID NCT05519644

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a ketone ester supplement can help people think clearly and perform physical tasks after four nights of reduced sleep. Researchers will give the drink to 60 military participants and measure their cognitive skills, reaction time, and marksmanship. The goal is to see if raising blood ketones can offset some of the negative effects of sleep deprivation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketone ester supplement

What this could lead to

If it works, this could point toward a simple drink that helps people stay sharp and accurate during short-term sleep loss.

What could go wrong

This is a small, early-stage study in healthy military personnel, so results may not apply to the general public. The supplement may not improve performance or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Sleep Deprivation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University

    Columbus, Ohio, 43210, United States