Ketones vs. sleeplessness: new study tests diet fix for tired brains
NCT ID NCT06075914
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a ketogenic diet or ketone supplements can reduce the mental and physical downsides of sleep loss. Sixty healthy adults ages 18–40 will cut their sleep by half for four nights while following either a ketogenic or Mediterranean diet, and taking either a ketone drink or a placebo. Researchers will measure thinking, marksmanship, agility, strength, and blood markers to see if ketones help protect against sleep deprivation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketogenic diet, Mediterranean diet, and ketone ester supplements
What this could lead to
If it works, this could point toward dietary strategies to help people—especially military personnel—stay sharp and perform well even when sleep is limited.
What could go wrong
This is a small, early-stage study (60 people) testing short-term effects in a controlled lab setting. Results may not apply to real-world conditions or to people with different health profiles.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••