Which airway method saves more kids? major trial aims to find out

NCT ID NCT06364280

Terminated Disease control Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests three ways emergency responders help children breathe: a bag-mask, a throat tube, or a breathing tube. It includes 3,000 children under 18 with cardiac arrest, severe injury, or breathing failure. The goal is to see which method leads to more days alive and out of the ICU within 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bag-valve-mask ventilation, supraglottic airway, and endotracheal intubation
What this could lead to: If successful, this could identify the best emergency airway method for children, potentially saving more lives and reducing ICU stays.
What could go wrong: The trial is currently suspended, and results may not apply to all settings. It compares existing techniques, so no new treatment is being developed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest CHILD syndrome Critical Illness injury Out-of-Hospital Cardiac Arrest respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILD, ONLY CRITICAL ILLNESS HEART ARREST, OUT-OF-HOSPITAL RESPIRATORY INSUFFICIENCY IN CHILDREN WOUNDS AND INJURIES

Contacts and locations

Locations

Children's National Hospital

Washington D.C., District of Columbia, 20010, United States
Dell Medical School, University of Texas at Austin

Austin, Texas, 78712, United States
Harbor-University of California Los Angeles Medical Center

Los Angeles, California, 90509, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Mecklenburg County Emergency Medical Services

Charlotte, North Carolina, 28208, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
University of Airzona

Tucson, Arizona, 85721, United States
University of California Davis

Sacramento, California, 95817, United States
University of Colordao

Aurora, Colorado, 80045, United States

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