CPAP may tame blood pressure in sleepy sleep apnea patients
NCT ID NCT05742360
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This study investigates whether using CPAP therapy for six months can reduce average 24-hour blood pressure in people with moderate-to-severe obstructive sleep apnea who also report excessive daytime sleepiness. Participants are adults aged 18-75 with elevated blood pressure and a confirmed sleep apnea diagnosis. The main goal is to measure changes in blood pressure using a portable monitor worn for a full day.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CPAP therapy (a device that delivers continuous positive airway pressure during sleep)
- What this could lead to
- If successful, this could show that treating sleep apnea with CPAP significantly lowers blood pressure in a specific subgroup of patients who are very sleepy.
- What could go wrong
- This is a medium-sized trial focused on a specific subtype, so results may not apply to all sleep apnea patients. Blood pressure improvements may be modest or not clinically significant.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Ohio State University - Martha Morehouse Medical Pavilion, Suite 2600
Columbus, Ohio, 43221, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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