Whole wheat vs. white bread: gut health showdown in prediabetes

NCT ID NCT05318183

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how eating whole wheat bread affects gut bacteria and health in adults with prediabetes. 65 participants will eat either whole wheat or white bread for two weeks, then provide stool, urine, and blood samples. The goal is to see if whole wheat can improve blood sugar and reduce inflammation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Whole wheat bread
What this could lead to
If it works, this could point toward dietary recommendations for managing prediabetes through gut health.
What could go wrong
This is a small, early-stage study with only 65 people over 2 weeks. Results may not apply to everyone or lead to clear health changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dysbiosis Endotoxemia Inflammation inflammatory disease prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University

    Columbus, Ohio, 43210, United States

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