Ohio State University

This study is testing if a one-time booster dose of the Gardasil-9 vaccine can help adults with recurrent respiratory papillomatosis (RRP) go longer between needed surgeries. RRP causes non-cancerous growths in the throat and airways, often requiring repeated procedures. The rese…

This study aims to find out if a shorter, 3-day course of preventive antibiotics works as well as the standard 7-day course for men having laser prostate surgery. It will enroll 250 men who already have a urinary catheter before their procedure. The main goal is to see if both ap…

This study aims to find out if a new nutrition supplement formula works better than a standard one for adults with cystic fibrosis. Researchers will compare how well the body absorbs and uses special versions of key nutrients like vitamins D and E, copper, and choline. About 60 p…

This study is testing whether a high-tech computer analysis of a child's eye can create a better glasses prescription than a standard eye exam. It will involve 24 children with Down syndrome, aged 5 to 12. Each child will try two different pairs of glasses for two months each to …

This study will test whether adding 12 virtual health coaching sessions over 16 weeks helps people recovering from heart attacks or heart failure. Researchers want to see if coaching improves weight management, reduces stress, increases medication adherence, and lowers hospital r…

This early-stage study is testing whether a combination of two existing drugs, dasatinib and quercetin, is safe and might help improve physical movement and thinking skills in older adults with progressive multiple sclerosis. The drugs aim to clear out old, damaged 'senescent' ce…

This study is testing a new support program designed for people with both a brain injury and a substance use disorder. The program includes screening for brain injury challenges and providing special accommodations during addiction therapy. Researchers want to see if this program…

This study aims to understand how a single dose of a drug related to psilocybin (the psychedelic compound in 'magic mushrooms') might help people with depression and anxiety. Researchers will give 40 participants either the drug or a placebo and use brain scans and questionnaires…

This study is for pregnant people with type 1 diabetes who use an insulin pump system. It compares two different blood sugar target ranges during labor and delivery. The goal is to see if a more relaxed target is just as safe for the newborn's first blood sugar level as the curre…

This study aims to understand how a support program called Ohio START helps rural families where a parent struggles with substance use. Researchers will follow 400 families for a year to see if connecting parents to nearby treatment services and providing guidance from mentors wh…

This study is testing whether eating one special cookie per day for eight weeks can improve sleep quality in overweight adults who have trouble sleeping. The cookies are made with an oil high in linoleic acid, a type of fat that may have health benefits. Researchers will measure …

This study is testing a home-based program to see if it can improve physical activity, sleep, and endurance in young children (ages 1-6) with severe motor delays, like cerebral palsy. Children will use a special supportive stander three times a week for eight weeks, with one week…

This study aims to understand how gum surgery affects inflammation levels in the bloodstream. Researchers will compare blood samples from 30 patients undergoing either surgical gum treatment or a standard non-surgical cleaning. By measuring specific inflammation markers at differ…

This study aims to better understand how early memory concerns progress over time in older adults from underserved communities. Researchers will follow 1,000 adults aged 50+ who have been diagnosed with early memory changes but not dementia. Participants will complete annual chec…

This study aims to better understand the normal healing process after a common gum graft surgery used to treat receding gums. Researchers will observe 15 patients by taking 3D scans of the graft area, measuring blood flow, collecting saliva samples, and having patients fill out q…

This study looks at existing dental records to understand how dental implants are positioned compared to natural teeth. Researchers will analyze X-rays from 400 patients who received molar implants to measure differences in angles and alignment. The goal is to gather information …