Ohio State University

This study looks at a surgery that adds bone to the upper jaw to support dental implants. Ten people will receive two different bone graft mixtures, one on each side of the jaw. After about 6 months of healing, the researchers will check bone quality and patient comfort to see wh…

This study tests a program that delivers fresh produce to the homes of pregnant women with type 1 or 2 diabetes who also struggle to get enough healthy food. Participants will also receive group education on diabetes, nutrition, and cooking, plus ongoing support for other needs. …

This study looks at 500 adults in the emergency room with dangerously low oxygen levels. It compares two non-invasive breathing supports: a pressurized face mask and high-flow nasal oxygen. The goal is to see which method improves survival, reduces time on a breathing machine, an…

This study aims to see if one nutrition supplement works better than another for adults with cystic fibrosis. Researchers will measure nutrient levels in the blood before and after 6 weeks of taking the supplement. The study involves 60 adults who have cystic fibrosis and take a …

This study tests a program called TBI-RECOVER for people who have both a traumatic brain injury and a substance use disorder. The program includes brain injury screening and special support to help patients stay in treatment. Researchers will see if the program helps patients att…

This study compares two new suction devices (FANS and CVAC) for removing medium to large kidney stones. About 159 adults with stones 8-20 mm will be randomly assigned to one of the tools. The main goal is to see which device leaves the kidney more stone-free, as shown on a CT sca…

This study looks at whether taking antibiotics for 3 days before prostate surgery works as well as taking them for 7 days to prevent infections. It involves 250 adults who have a urinary catheter and are getting a specific type of prostate surgery called HoLEP. The goal is to see…

This study tests whether a single booster dose of the Gardasil-9 vaccine can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a condition where non-cancerous growths recur in the airway. Researchers will enroll 50 adults who have alr…

This study looks at whether 12 virtual health coaching sessions over 16 weeks can help people with heart disease (like heart failure or a heart attack) improve their health, lower stress, and reduce hospital readmissions. About 70 adults will take part, comparing coaching plus st…

This early-stage study tests whether a combination of two drugs, dasatinib and quercetin, can safely improve physical and mental function in adults aged 50-85 with secondary progressive multiple sclerosis (MS). Participants take the drugs every two weeks for three months. The goa…

This study compares two ways to prescribe glasses for children with Down syndrome, ages 5 to 12. One method uses computer analysis of eye images, the other uses standard clinical exams. The goal is to see which approach gives better vision. The study involves 24 children and is n…

This study tests whether a single oral dose of CYB003, a drug related to psilocybin, can help ease symptoms of depression and anxiety in 40 adults with major depressive disorder. Participants will receive either the drug or a placebo, and researchers will use brain scans and ques…

This study looks at whether eating healthy cookies made with a special oil (linoleic acid) for 8 weeks can improve sleep quality in overweight adults who have trouble sleeping. Researchers will measure sleep changes, blood fat levels, and how well people stick to eating the cooki…

This study will measure stress and inflammation markers in the blood of 30 adults having gum surgery or a non-surgical gum treatment. Researchers want to see how these markers change during and after the procedure. Participants will give blood samples before, during, and after th…

This study will follow 1,000 older adults (age 50+) from under-resourced communities who have early memory concerns. Researchers will collect health data, brain scans, and samples over time to better understand how dementia develops. No treatment or medication is given—the goal i…

This study observes 400 parents in rural Ohio who are part of the Ohio START program, which connects them to substance use treatment and peer mentors. Researchers want to see if having services nearby and strong social support helps parents recover and improves their children's h…

This study looks at dental records to see how the angle of a single molar implant compares to the original tooth or the same tooth on the other side. No new participants are enrolled; researchers will review existing images from about 400 patients. The goal is to understand typic…