Ohio State University

This study tests whether adding an 8-week online mindfulness program, called Mindfulness in Motion, to usual care helps people with high blood pressure improve their blood pressure, weight, stress, sleep, and well-being. Participants will be randomly assigned to either the mindfu…

This study will test whether a nutrition supplement with different forms of certain nutrients works better than standard supplements for adults with cystic fibrosis. Sixty participants will take the supplement for six weeks, and researchers will measure nutrient levels in their b…

This study tests whether adding Platelet-Rich Fibrin (PRF) – a natural substance made from your own blood – to a bone graft helps the extraction site heal faster and grow more bone. Fourteen adults needing two tooth extractions will receive PRF plus bone graft in one socket and s…

This study compares two common surgical techniques used to uncover dental implants during a second-stage procedure: the Apically Positioned Flap and the Rolled Flap Technique. Researchers want to see which method leads to better gum healing, thickness, and appearance over one yea…

This study looks at a surgery that adds bone to the upper jaw to support dental implants. Ten healthy, non-smoking adults will receive two different bone graft mixtures, one on each side of their jaw. The goal is to see which mixture leads to better bone healing and strength over…

This study tests whether a one-time booster dose of the Gardasil-9 vaccine can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a condition where non-cancerous growths keep coming back in the airway. Researchers will enroll 50 adults…

This study tests whether taking antibiotics for 3 days before prostate surgery works as well as the usual 7 days to prevent infections like urinary tract infections or sepsis. The trial includes 250 adults who have a urinary catheter and are scheduled for a specific prostate proc…

This trial is testing a new type of therapy called Augmented Depression Therapy (ADepT) for adults with major depression. ADepT blends techniques from cognitive, behavioral, and acceptance-based treatments to help manage depression and increase wellbeing. The study will enroll 40…

This clinical trial tests whether coating a breathing tube with 5% lidocaine ointment before insertion reduces coughing and throat irritation as patients wake up from anesthesia. Adults aged 18 to 90 undergoing surgery with general anesthesia are randomly assigned to receive eith…

This study looks at whether 12 virtual health coaching sessions over 16 weeks can help people with heart disease (like heart failure or a heart attack) improve their health, reduce stress, and lower the chance of going back to the hospital. About 70 adults will take part, and the…

This study looks at whether monthly group medical visits focused on lifestyle medicine and mindfulness can help women ages 40-60 going through perimenopause or menopause. Over eight months, participants will learn about healthy living, practice mindfulness, and have check-ups to …

This study tests whether eating at least 6 servings of fermented foods daily for 10 weeks can improve bowel function and gut health in adults with chronic spinal cord injury. Participants will be randomly assigned to either a high-fermented-food diet or a control diet. The resear…

This pilot study will test whether a weekly 60-minute sound bowl meditation, offered for six weeks, can lower stress and anxiety in unpaid caregivers. Forty adult caregivers who have been helping a chronically ill or disabled family member or friend for at least six months will p…

This study compares two new suction-based tools (FANS and CVAC) for removing medium-to-large kidney stones. About 159 adults with stones 8-20 mm will be randomly assigned to one device. The goal is to see which scope clears more stones completely, as shown on CT scans.

This study looks at whether eating special healthy cookies high in linoleic acid (a type of fat) for 8 weeks can improve sleep quality in overweight adults who have trouble sleeping. Researchers will measure sleep changes, blood fat levels, and how well people stick to eating the…

This early-stage trial tests whether a combination of two drugs, dasatinib and quercetin, can safely remove aged, damaged cells that may contribute to inflammation and nerve damage in people with secondary progressive multiple sclerosis (MS). The study enrolls 30 adults aged 50-8…

This study looks at how gum surgery changes inflammation markers in the blood. Researchers will take blood samples from 30 adults before, during, and after dental procedures. The goal is to see if surgical stress causes a different inflammatory response compared to non-surgical c…

This study looks at people with chronic pain who are trying spinal cord stimulation (SCS) as part of their normal care. Researchers track daily pain scores, satisfaction, and the timing of decisions about getting a permanent implant. The goal is to find the shortest trial period …

This study tests whether a computer simulation can help pharmacists and pharmacy students better understand the pain struggles of sickle cell disease patients. About 200 healthcare professionals will use a point-of-view simulation and then complete surveys to see if their misconc…

This study will compare two non-invasive breathing support methods—a face mask that pushes air in and a special nasal tube that delivers high-flow oxygen—for adults in the emergency room with dangerously low blood oxygen. About 500 participants will be randomly assigned to one me…

This study will follow 1,000 older adults from under-resourced communities who have early memory concerns or mild cognitive impairment. Participants will be monitored through phone or video visits, with data collected on thinking skills, brain scans, and blood samples. The goal i…