ER study to determine best breathing aid for oxygen crisis

NCT ID NCT07558265

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two non-invasive breathing support methods—a face mask that pushes air in and a special nasal tube that delivers high-flow oxygen—for adults in the emergency room with dangerously low blood oxygen. About 500 participants will be randomly assigned to one method, and researchers will track survival, days on a breathing machine, and how long support is needed. The goal is to find which approach works best as a first treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors choose the best initial breathing support for emergency patients with low oxygen levels, potentially improving survival and reducing time on a ventilator.

What could go wrong

This is an early-stage comparison study, not testing a new drug or cure. Results may not apply to all patients, and individual responses to the devices can vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome acute respiratory failure adult acute respiratory distress syndrome chronic obstructive pulmonary disease respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • OSU Wexner Medical Center

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State East Hospital

    Columbus, Ohio, 43203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••