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ER study to determine best breathing aid for oxygen crisis

NCT ID NCT07558265

Not yet recruiting Knowledge-focused Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two non-invasive breathing support methods—a face mask that pushes air in and a special nasal tube that delivers high-flow oxygen—for adults in the emergency room with dangerously low blood oxygen. About 500 participants will be randomly assigned to one method, and researchers will track survival, days on a breathing machine, and how long support is needed. The goal is to find which approach works best as a first treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors choose the best initial breathing support for emergency patients with low oxygen levels, potentially improving survival and reducing time on a ventilator.
What could go wrong
This is an early-stage comparison study, not testing a new drug or cure. Results may not apply to all patients, and individual responses to the devices can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome acute respiratory failure adult acute respiratory distress syndrome chronic obstructive pulmonary disease respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE HYPOXIC RESPIRATORY FAILURE ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)

Contacts and locations

Locations

  • OSU Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Ohio State East Hospital

    Columbus, Ohio, 43203, United States

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