Immune clues may unlock better ECMO care for lung failure patients

NCT ID NCT07726940

Recruiting now Disease control Sponsor: Southeast University, China Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial studies adults with moderate-to-severe acute respiratory distress syndrome (ARDS) who need ECMO life support. Researchers aim to classify patients into immune-based subtypes, understand why complications like kidney injury and bleeding occur, and develop a personalized, full-cycle ECMO management plan. The goal is to improve survival and recovery by tailoring ventilation and ECMO strategies to each patient's immune profile.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: extracorporeal membrane oxygenation (ECMO) support
What this could lead to: If successful, this could lead to a precision, full-cycle ECMO management pathway that reduces complications and improves survival in severe ARDS.
What could go wrong: This is a large mechanistic study, not a simple drug trial. The complexity of immune phenotyping and ECMO management means results may take years to translate into bedside practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)

Contacts and locations

Locations

Affiliated Hospital of Nantong University
NOT_YET_RECRUITING

Nantong, China
Affiliated Hospital of Qinghai University
NOT_YET_RECRUITING

Xining, China
Affiliated Hospital of Xuzhou Medical University
NOT_YET_RECRUITING

Xuzhou, China
Beijing Anzhen Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, China
Fujian Provincial Hospital
RECRUITING

Fuzhou, Fujian, China
General Hospital of Ningxia Medical University
NOT_YET_RECRUITING

Ningxiang, China
Hangzhou First People's Hospital, Westlake University School of Medicine
NOT_YET_RECRUITING

Hangzhou, China
Henan Provincial People's Hospital
RECRUITING

Zhengzhou, China
Huai'an First People's Hospital
NOT_YET_RECRUITING

Huai'an, China
Jiangsu Province Hospital
NOT_YET_RECRUITING

Nanjing, China
Kunshan First People's Hospital
NOT_YET_RECRUITING

Kunshan, China
Liuzhou People's Hospital
RECRUITING

Liuzhou, China
Nanjing Drum Tower Hospital
RECRUITING

Nanjing, China
People's Hospital of Guangxi Zhuang Autonomous Region
NOT_YET_RECRUITING

Naning, China
Qilu Hospital of Shandong University
RECRUITING

Jinan, Shandong, China
Quzhou People's Hospital
RECRUITING

Quzhou, China
Sichuan Provincial People's Hospital
RECRUITING

Chengdu, Sichuan, China
Subei People's Hospital
NOT_YET_RECRUITING

Yangzhou, China
Suining Central Hospital
NOT_YET_RECRUITING

Suining, China
The First Affiliated Hospital of Guangxi Medical University
NOT_YET_RECRUITING

Nanning, China
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, China
The First Affiliated Hospital of Harbin Medical University
NOT_YET_RECRUITING

Ha’erbin, China
The First Affiliated Hospital of Soochow University
NOT_YET_RECRUITING

Suzhou, China
The First Affiliated Hospital of Xiamen University
NOT_YET_RECRUITING

Xiamen, China
The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITING

Zhengzhou, China
The First Hospital of Lanzhou University
NOT_YET_RECRUITING

Lanzhou, China
The First People's Hospital of Chenzhou
RECRUITING

Chenzhou, China
The First People's Hospital of Lianyungang
NOT_YET_RECRUITING

Lianyungang, China
The Second Affiliated Hospital of Dalian Medical University
NOT_YET_RECRUITING

Dalian, China
The Second Affiliated Hospital of Guangxi Medical University
NOT_YET_RECRUITING

Nanning, China
The Second Affiliated Hospital of Harbin Medical University
RECRUITING

Ha’erbin, China
The Second Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, China
The Second Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, China
The Second Hospital of Jilin University
NOT_YET_RECRUITING

Changchun, China
West China Tianfu Hospital, Sichuan University
NOT_YET_RECRUITING

Sichuan, China
Wuxi People's Hospital
RECRUITING

Wuxi, China
Xinyang Central Hospital
NOT_YET_RECRUITING

Xinyang, China
Zhongda Hospital, Southeast University
RECRUITING

Nanjing, Jiangsu, 210009, China
Zhongshan Hospital of Traditional Chinese Medicine
RECRUITING

Zhongshan, China

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