A therapy that aims to boost wellbeing, not just ease symptoms — a trial puts it to the test

NCT ID NCT07733310

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial is testing a new type of therapy called Augmented Depression Therapy (ADepT) for adults with major depression. ADepT blends techniques from cognitive, behavioral, and acceptance-based treatments to help manage depression and increase wellbeing. The study will enroll 40 participants who will receive 15 weekly therapy sessions plus optional booster sessions over 12 months. Researchers want to see if patients find the therapy acceptable and whether it reduces depressive symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a behavioral therapy called Augmented Depression Therapy (ADepT) that combines cognitive, behavioral, and acceptance-based techniques
What this could lead to
If it works, this could offer a new, wellbeing-focused therapy option for people with depression.
What could go wrong
This is a small, early case series with only 40 participants, so results may not apply broadly. The therapy is time-intensive and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43214, United States

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