Could a single X-Ray tame COVID-19 lung inflammation?
NCT ID NCT04466683
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether a single, low dose of radiation to the chest can reduce lung inflammation in hospitalized COVID-19 pneumonia patients. Researchers compare two radiation doses (35 cGy and 100 cGy) to standard care. The goal is to see if this treatment lowers the need for ventilators, shortens hospital stays, and reduces deaths.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low-dose radiation (whole thorax radiotherapy)
- What this could lead to
- If it works, this could offer a simple, one-time treatment to reduce severe lung inflammation in COVID-19 pneumonia and lower the need for ventilators.
- What could go wrong
- This is a small, early-phase trial with only 37 participants, so results may not apply broadly. Radiation to the lungs carries unknown risks, and the treatment may not improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boca Raton Regional Hospital Lynn Cancer Institute
Boca Raton, Florida, 33486, United States
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Hospital Universitario San Ignacio
Bogotá, Colombia
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Indiana University School of Medicine
Indianapolis, Indiana, 46202, United States
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Lowell General Hospital Cancer Center
Lowell, Massachusetts, 01854, United States
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Loyola University Chicago
Maywood, Illinois, 60153, United States
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Miami Cancer Institute
Miami, Florida, 33176, United States
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Ohio State University James Cancer Hospital
Columbus, Ohio, 43210, United States
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