New tests could reveal how SMA progresses in adults

NCT ID NCT04139343

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at 67 adults with spinal muscular atrophy (SMA) types 2 and 3 to see if special electrical tests (MUNE and CMAP) can track nerve loss over time. The goal was to find better ways to measure how the disease changes, not to test a treatment. Participants had genetic testing to confirm SMA and were followed with these non-invasive tests.

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Conditions

The condition(s) this trial relates to.

spinal muscular atrophy spinal muscular atrophy, type II spinal muscular atrophy, type III

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University Medical Center

    Columbus, Ohio, 43210, United States