Fish oil supplements show promise for stubborn leg ulcers

NCT ID NCT03576989

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking fish oil supplements (EPA and DHA) could help heal chronic venous leg ulcers in adults aged 55 and older. The idea was that fish oil might reduce inflammation at the wound site, allowing the ulcer to heal. Researchers measured changes in blood markers of inflammation and wound size over 12 weeks in 96 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fish oil (EPA and DHA)

What this could lead to

If it works, this could point toward a simple, low-cost way to help heal stubborn leg ulcers in older adults.

What could go wrong

This is a small, early-stage study focused on measuring inflammation markers, not actual healing rates. The results may not lead to a proven treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic ulcer of skin injury Leg Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University College of Nursing

    Columbus, Ohio, 43210, United States